Comparison of Two Algorithms for Analysis of Perfusion Computed Tomography Data for Evaluation of Cerebral Microcirculation in Chronic Subdural Hematoma.

Comparison of Two Algorithms for Analysis of Perfusion Computed Tomography Data for Evaluation of Cerebral Microcirculation in Chronic Subdural Hematoma.
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两种灌注计算机断层扫描数据分析算法的比较,用于评估慢性硬膜下血肿的脑微循环。

DOI:
10.1007/978-3-319-38810-6_53
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发表时间:
2016
影响因子:
--
通讯作者:
Bragin,DenisE
Bragin,DenisE
中科院分区:
医学4区
文献类型:
--
作者:
Trofimov,AlexeyO;Kalentiev,George;Voennov,Oleg;Yuriev,Michail;Agarkova,Darya;Trofimova,Svetlana;Bragin,DenisE

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本工作的目的是比较两种算法的灌注计算机断层扫描(PCT)数据分析的慢性硬膜下血肿(CSDH)病灶周围区的脑微循环的评价。20例多发伤后CSDH患者纳入本研究。在不使用和使用灌注计算模式(不包括血管像素“远程血管”(RV))的情况下,分别在CSDH下方的皮质脑区域(1区)和相应的对侧脑半球(2区)中定量评估相同的PCT数据;第1和第2种分析方法。与第1种分析方法中1区灌注指数的正常值相比,CBV和CBF显著增加(p< 0.01),MTT和TTP无显著增加。使用RV模式(第2分析方法)显示第2区微循环血流中灌注参数无统计学可靠变化。微循环血流灌注的维持反映了CSDH患者脑血流自动调节功能的保留。
The aim of this work was comparison of two algorithms of perfusion computed tomography (PCT) data analysis for evaluation of cerebral microcirculation in the perifocal zone of chronic subdural hematoma (CSDH). Twenty patients with CSDH after polytrauma were included in the study. The same PCT data were assessed quantitatively in cortical brain region beneath the CSDH (zone 1), and in the corresponding contralateral brain hemisphere (zone 2) without and with the use of perfusion calculation mode excluding vascular pixel ‘Remote Vessels’ (RV); 1st and 2nd analysis method, respectively. Comparison with normal values for perfusion indices in the zone 1 in the 1st analysis method showed a significant (p< 0.01) increase in CBV and CBF, and no significant increase in MTT and TTP. Use of the RV mode (2nd analysis method) showed no statistically reliable change of perfusion parameters in the microcirculatory blood flow of the 2nd zone. Maintenance of microcirculatory blood flow perfusion reflects the preservation of cerebral blood flow autoregulation in patients with CSDH.
DOI: 10.1007/s12028-013-9830-5
发表时间: 2013-06-01
期刊: NEUROCRITICAL CARE
影响因子: 3.5
作者:
Varsos, Georgios V.;de Riva, Nicolas;Czosnyka, Marek
通讯作者: Czosnyka, Marek