Cerebellar atrophy in temporal lobe epilepsy affects procedural memory
Cerebellar atrophy in temporal lobe epilepsy affects procedural memory
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DOI：
10.1212/01.wnl.0000145774.89754.0c
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发表时间：
2004-12-14
期刊：
影响因子：
9.9
通讯作者：
Dow, C
中科院分区：
文献类型：
--
作者：
Hermann, B;Seidenberg, M;Dow, C
作者研究了由小脑介导的认知功能，经典眨眼条件反射及其与健康对照组（n = 59）和颞叶癫痫受试者（n = 77）小脑体积的关系。对照组表现出更好的条件反射，更大的小脑体积，以及在癫痫患者中未观察到的条件反射和小脑体积之间的关联。这些发现为癫痫小脑萎缩影响程序性记忆的假设提供了支持。
The authors examined a cognitive function mediated by the cerebellum, classical eyeblink conditioning, and its relationship to cerebellar volume in healthy controls ( n = 59) and temporal lobe epilepsy subjects ( n = 77). Controls demonstrated better conditioning, larger cerebellar volumes, and an association between conditioning and cerebellar volume that was not observed in epilepsy patients. These findings provide support for the hypothesis that cerebellar atrophy in epilepsy affects procedural memory.