Diffusion-weighted MR imaging abnormalities in pediatric patients with surgically-treated intracranial mass lesions.
Diffusion-weighted MR imaging abnormalities in pediatric patients with surgically-treated intracranial mass lesions.
复制标题
经手术治疗的颅内肿块病变的儿科患者的弥散加权磁共振成像异常。
DOI：
10.1007/s11060-006-9127-z
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发表时间：
2006
影响因子：
3.9
通讯作者：
Cha,Soonmee
中科院分区：
文献类型：
--
作者：
Smith,JustinS;Lin,Henry;Mayo,MaryCatherine;Bannerjee,Anuradha;Gupta,Nalin;Perry,Victor;Cha,Soonmee
弥散加权成像（DWI）是一种测量体内水扩散程度的磁共振成像（MRI）技术。DWI异常经常在成人胶质瘤手术切除后即刻的术后成像中观察到。这些异常随后表现为对比增强，这可能与病变复发混淆。本研究的目的是探讨这些术后异常的发生在儿科患者颅内肿块infertiles. MethodsThirteen连续患者≤18岁的新诊断的颅内肿块病变进行MRI，包括DWI，手术治疗前和手术后立即。幕上和幕下病变分别在22和11例患者中确定。浸润性和非浸润性，以及良性和恶性病变，包括在内。术后影像学检查显示20例（61%）病例的切除腔附近存在扩散减少区域。这些区域的中位体积为1.7 cm 3（范围0.3 cm 3 -12.0 cm 3）。18例中9例的后续成像研究显示DWI异常对应区域的对比度增强。没有可归因于任何扩散异常的临床缺陷。这些异常的发生和病变是否浸润，非浸润，良性，或malignant.ConclusionsDWI异常立即术后MRI是常见的手术后新诊断的颅内肿块病变的儿科患者之间没有关联。术后局部增强可能与某些病变的复发相混淆。我们的研究表明，术后即刻DWI有助于解释脑肿瘤手术后儿童后续成像中新的局灶性对比度增强区域。
IntroductionDiffusion-weighted imaging (DWI) is a magnetic resonance imaging (MRI) technique that measures the degree of water diffusionin vivo. DWI abnormalities are frequently observed on immediate postoperative imaging following surgical resection of gliomas in adults. These abnormalities subsequently demonstrate contrast enhancement, which may be confused with lesion recurrence. The purpose of this study was to investigate the occurrence of these postoperative abnormalities in pediatric patients with intracranial mass lesions.MethodsThirty-three consecutive patients ≤18 years old with a newly diagnosed intracranial mass lesion underwent MRI, including DWI, before and immediately after surgical treatment.ResultsThe median patient age was 9.9 years (range 0.2–18 years). Supratentorial and infratentorial lesions were identified in 22 and 11 patients, respectively. Infiltrative and noninfiltrative, as well as benign and malignant lesions, were included. Postoperative imaging demonstrated areas of reduced diffusion adjacent to the resection cavity in 20 (61%) cases. The median volume of these areas was 1.7 cm3(range 0.3 cm3–12.0 cm3). Subsequent imaging studies in 9 of the 18 cases showed contrast enhancement in the area corresponding to the DWI abnormality. There were no clinical deficits attributable to any of the diffusion abnormalities. There was no association between the occurrence of these abnormalities and whether the lesion was infiltrative, non-infiltrative, benign, or malignant.ConclusionsDWI abnormality on immediate postoperative MRI is common following surgery for newly diagnosed intracranial mass lesions in pediatric patients. Focal contrast enhancement in the postoperative period may be confused with recurrence for some lesions. Our study suggests that immediate postoperative DWI is useful in interpreting new areas of focal contrast enhancement on subsequent imaging in children who have had surgery for brain tumors.