Equilibrium shift in solution: molecular shape recognition and precipitation of a synthetic double helix using helicene-grafted silica nanoparticles.
Equilibrium shift in solution: molecular shape recognition and precipitation of a synthetic double helix using helicene-grafted silica nanoparticles.
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DOI：
10.1002/chem.201303486
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发表时间：
2014-01
期刊：
影响因子：
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通讯作者：
Masamichi Miyagawa;W. Ichinose;M. Yamaguchi
中科院分区：
文献类型：
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作者：
Masamichi Miyagawa;W. Ichinose;M. Yamaguchi
接枝(P)-螺旋烯的手性二氧化硅纳米颗粒（70 nm）在溶液中识别出双螺旋和无规螺旋(P)-乙基螺旋烯低聚物的分子形状。(P)纳米粒子和双螺旋结构的混合物比(P)纳米粒子和随机线圈的混合物沉淀得快得多，而且沉淀只包含双螺旋结构。(P)-纳米颗粒和(P)-乙基螺旋烯五聚体的混合物在70℃加热时可逆地分散在三氟甲基苯中，在25℃冷却时沉淀。当(P)-纳米粒子处理溶液中双螺旋和随机螺旋的10:90平衡混合物时，双螺旋的析出率为53%，并伴有平衡移位。
Chiral silica nanoparticles (70 nm) grafted with (P)-helicene recognized the molecular shape of double helix and random coil (P)-ethynylhelicene oligomers in solution. A mixture of the (P)-nanoparticles and double helix precipitated much faster than a mixture of the (P)-nanoparticles and random coil, and the precipitate contained only the double helix. The mixture of the (P)-nanoparticles and (P)-ethynylhelicene pentamer reversibly dispersed in trifluoromethylbenzene upon heating at 70 °C and precipitated upon cooling at 25 °C. When a 10:90 equilibrium mixture of the double helix and random coil in solution was treated with the (P)-nanoparticles, the double helix was precipitated in 53% yield and was accompanied by equilibrium shift.