Prevalence and correlates of frailty among community-dwelling older men and women: findings from the Hertfordshire Cohort Study
Prevalence and correlates of frailty among community-dwelling older men and women: findings from the Hertfordshire Cohort Study
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DOI：
10.1093/ageing/afp204
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发表时间：
2010-03-01
期刊：
影响因子：
6.7
通讯作者：
Sayer, Avan Aihie
中科院分区：
文献类型：
--
作者：
Syddall, Holly;Roberts, Helen C.;Sayer, Avan Aihie
方法：对参加英国赫特福德郡队列研究的社区青年(-74岁)、男性(n=320)和女性(n=318)进行Fry定义的脆弱调查。结果：脆弱的患病率女性为8.5%，男性为4.1%(P=0.02)。在男性中，年龄较大(P=0.009.0 5)、离校年龄较早(P=0.0 5)、没有拥有/抵押住房(与拥有/抵押贷款的人相比，其OR值为3.4 5[95%可信区间1.0 1-11.81]，P=0.0 5)，汽车可获得性减少(每单位可用汽车数量减少3.5 7，95%可信区间1.32，10.0，P=0.0 1)与脆弱风险增加有关。在女性中，不拥有或抵押自己的房子(P=0.02)与虚弱有关。除男性有车可用外(P=0.03)，所有的关联在调整共病因素后都不显著(P>；0.05)。结论：即使在英国社区居住的年轻人和女性中，虚弱也并不少见。在脆弱方面存在着社会不平等，这似乎是由共同发病造成的。
Methods: frailty, defined by Fried, was examined among community-dwelling young-old (64-74 years) men (n = 320) and women (n = 318) who participated in the Hertfordshire Cohort Study, UK.Results: the prevalence of frailty was 8.5% among women and 4.1% among men (P = 0.02). Among men, older age (P = 0.009), younger age of leaving education (P = 0.05), not owning/mortgaging one's home (odds ratio [OR] for frailty 3.45 [95% confidence interval {CI} 1.01-11.81], P = 0.05, in comparison with owner/mortgage occupiers) and reduced car availability (OR for frailty 3.57 per unit decrease in number of cars available [95% CI 1.32, 10.0], P = 0.01) were associated with increased odds of frailty. Among women, not owning/mortgaging one's home (P = 0.02) was associated with frailty. With the exception of car availability among men (P = 0.03), all associations were non-significant (P > 0.05) after adjustment for co-morbidity.Conclusions: frailty is not uncommon even among community-dwelling young-old men and women in the UK. There are social inequalities in frailty which appear to be mediated by co-morbidity.