Computational study on hemodynamic effects of left superior pulmonary vein resection and associated physiological changes in the left atrium after left upper lobectomy
Computational study on hemodynamic effects of left superior pulmonary vein resection and associated physiological changes in the left atrium after left upper lobectomy
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DOI：
10.1080/10255842.2023.2178258
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发表时间：
2023-02-08
影响因子：
1.6
通讯作者：
Wada，Shiego
中科院分区：
文献类型：
--
作者：
Yi，Wentao;Otani，Tomohiro;Wada，Shiego
左上叶切除术（LUL）和左上级肺静脉（LSPV）切除术改变了与血栓形成相关的左心房（LA）生理状态和LA血流动力学，尽管对这一潜在机制知之甚少。因此，我们使用基于四维计算机断层扫描图像的计算模拟研究了LSPV切除术和相关LA生理变化对LA血流动力学的影响。审议了三种情况：从计算机断层扫描图像中提取LUL和人工LSPV切除术前后的LA，无生理变化。三个病例的比较表明，与LSPV切除相关的生理变化可能是影响LUL后LA血流动力学的因素。
Left upper lobectomy (LUL) with left superior pulmonary vein (LSPV) resection alters the left atrium (LA) physiological states and LA hemodynamics associated with thrombosis, although this underlying mechanism is poorly understood. Therefore, we investigated the effects of LSPV resection and associated LA physiological changes on LA hemodynamics using four-dimensional computed tomography image-based computational simulations. Three cases were considered: the LA before and after LUL extracted from computed tomography images and artificial LSPV resection without physiological changes. Comparisons among the three cases demonstrated that physiological changes associated with LSPV resection are the possible factors that affect the LA hemodynamics after LUL.