Prediction of breast cancer size by ultrasound, mammography and core biopsy
Prediction of breast cancer size by ultrasound, mammography and core biopsy
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DOI：
10.1016/j.breast.2004.05.005
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发表时间：
2004-08-01
期刊：
影响因子：
3.9
通讯作者：
Morrow, M
中科院分区：
文献类型：
--
作者：
Golshan, M;Fung, BB;Morrow, M
新辅助化疗和非手术肿瘤消融术依赖于成像研究来确定肿瘤大小。在这项研究中，在202例I期和II期乳腺癌患者中检查了超声（US）乳腺X线摄影和芯活检在确定肿瘤大小方面的准确性。确定肿瘤大小最准确的单一方法是乳腺X线摄影，相关系数（R）为0.66，其次是US（r = 0.48）和芯活检（r = 0.28）。小叶癌的大小测量不如导管癌准确。三种方法的联合应用使25%的> 1 cm肿瘤分期过低，10%的< 1 cm肿瘤分期过高。无法准确确定肿瘤大小对非手术消融的使用具有重要意义。(C)2004 Elsevier Ltd.保留所有权利。
Neoadjuvant chemotherapy and non-surgical tumor ablation rely upon imaging studies to determine tumor size. In this study the accuracy of ultrasound (US) mammography and core biopsy in determining tumor size was examined in 202 patients with Stages I and II breast cancer. The most accurate single modality for determining tumor size was mammography with a correlation coefficient(R) of 0.66, followed by US (r = 0.48) and core biopsy (r = 0.28). Size measurements were Less accurate in lobular than ductal cancers. The combination of the three modalities understaged 25% of the tumors > 1 cm in size, and overstaged 10% of those < 1 cm. The inability to accurately determine tumor size has important implications for the use of non-surgical ablation. (C) 2004 Elsevier Ltd. ALL rights reserved.