Botulinum toxin treatment of axial and cervical dystonia
Botulinum toxin treatment of axial and cervical dystonia
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DOI：
10.1080/01421590701568262
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发表时间：
2007-12-15
影响因子：
2.2
通讯作者：
Dressler, Dirk
中科院分区：
文献类型：
--
作者：
Benecke, Reiner;Dressler, Dirk
轴性躯干肌张力障碍的特征是躯干姿势异常，常伴有肌阵挛性运动活动。颈性肌张力障碍是一种运动综合征，其特征是由于某些肌肉的强直性不自主收缩而导致的头部和颈部姿势异常，通常伴有肌阵挛或震颤运动。肌内注射肉毒杆菌毒素是治疗颈部肌张力障碍的第一线治疗，在轴性躯干肌张力障碍中，肉毒杆菌毒素治疗仅用于轻度形式。本文介绍了其理论背景、实践方面和疗效结果，特别是在颈部肌张力障碍方面。治疗轴性躯干肌张力障碍，只是简要讨论了在本审查的开始。
Axial truncal dystonia is characterized by an abnormal trunk posture often superimposed by myoclonic motor activities. Cervical dystonia is a motor syndrome characterized by abnormal head and neck posture due to tonic involuntary contractions in a certain set of muscles often superimposed by myoclonic or tremolous movements. Intramuscular injection of botulinum toxin is the first line treatment in cervical dystonia, in axial truncal dystonias botulinum toxin therapy is used only in mild forms. In this review the theoretical background, practical aspects and efficacy results especially in cervical dystonia are presented. Treatment of axial trunk dystonia is only briefly discussed at the beginning of this review.