Sugar-Fueled Dissipative Living Materials
Sugar-Fueled Dissipative Living Materials
复制标题
以糖为燃料的耗散生命材料
DOI：
10.1021/jacs.2c11122
复制
发表时间：
2023
影响因子：
15
通讯作者：
Sim, Seunghyun
中科院分区：
文献类型：
--
作者：
Jo, Hyuna;Selmani, Serxho;Guan, Zhibin;Sim, Seunghyun
生物学中的耗散行为是由活细胞控制的燃料驱动过程，它们塑造了生物材料的结构和功能复杂性。这一概念激发了各种形式的合成耗散材料的发展，这些材料由化学或物理燃料的时间依赖性消耗控制，例如反应性化学物质、光和电。迄今为止，具有由其组成细胞的燃料消耗直接控制的耗散行为的合成生物材料是前所未有的。本文报道了表皮葡萄球菌和遥爪嵌段共聚物等生物材料的化学燃料驱动耗散行为。宏观相变是由d-葡萄糖控制的，它具有竞争性分解剂和活细胞生物燃料源的双重作用。我们的工作是构建一个综合耗散生命系统的重要一步，并提供了一个新的工具和知识来设计新兴的生命材料。
Dissipative behaviors in biology are fuel-driven processes controlled by living cells, and they shape the structural and functional complexities in biological materials. This concept has inspired the development of various forms of synthetic dissipative materials controlled by time-dependent consumption of chemical or physical fuels, such as reactive chemical species, light, and electricity. To date, synthetic living materials featuring dissipative behaviors directly controlled by the fuel consumption of their constituent cells is unprecedented. In this paper, we report a chemical fuel-driven dissipative behavior of living materials comprisingStaphylococcus epidermidisand telechelic block copolymers. The macroscopic phase transition is controlled byd-glucose which serves a dual role of a competitive disassembling agent and a biological fuel source for living cells. Our work is a significant step toward constructing a synthetic dissipative living system and provides a new tool and knowledge to design emergent living materials.