Neuronal phosphoproteins: physiological and clinical implications.
Neuronal phosphoproteins: physiological and clinical implications.
复制标题
神经元磷蛋白：生理和临床意义。
DOI：
10.1126/science.6474180
复制
发表时间：
1984
期刊：
影响因子：
--
通讯作者：
Greengard,P
中科院分区：
文献类型：
--
作者：
Nestler,EJ;Walaas,SI;Greengard,P
神经组织中存在大量神经元特异性磷蛋白，这支持了蛋白磷酸化在神经元功能中发挥多种作用的观点。其中几种磷蛋白的生理学意义已经确定。一些神经元磷蛋白在整个神经系统中被检测到，而其他的分布仅限于一种或几种神经元细胞类型。这些不同的神经元特异性磷蛋白在神经系统的生理学、解剖学、发育生物学和病理生理学的研究中被证明是有价值的。
The presence of a great variety of neuron-specific phosphoproteins in nervous tissue supports the view that protein phosphorylation plays many roles in neuronal function. The physiological significance of several of these phosphoproteins has already been established. Some neuronal phosphoproteins have been detected throughout the entire nervous system, whereas the distribution of others is limited to one or a few neuronal cell types. These various neuron-specific phosphoproteins are proving of value in the study of the physiology, anatomy, developmental biology, and pathophysiology of the nervous system.