Vitreoretinal juncture. Synchysis senilis and posterior vitreous detachment.

Vitreoretinal juncture. Synchysis senilis and posterior vitreous detachment.
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DOI:
10.1016/s0161-6420(82)34610-2
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发表时间:
1982-12
期刊:
影响因子:
13.7
通讯作者:
R. Foos;N. Wheeler
R. Foos;N. Wheeler
中科院分区:
医学1区
文献类型:
--
作者:
R. Foos;N. Wheeler

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对2246例(4492只眼)尸检者的玻璃体老年性融合进行了定量研究,并对其与玻璃体后脱离(PVD)的关系进行了统计分析,排除了除衰老外其他原因引起的玻璃体老年性融合或PVD。根据空气悬浮技术判断的破坏程度,联结功能分级为0.00005~6级;联结功能随年龄增长而增加(P<0.05)。PVD也与年龄有关,在第七个十年变得显著(27%),在第八个十年达到顶峰(63%)。当绘制出每一级联结的PVD比率时,联结3级(50%破坏)和4级(67%)之间有显著的上升(P<0.00005);当考虑到年龄时,这种趋势也很明显。这些定量数据重申了联结在孔源性PVD中的作用,并表明在某些事件启动PVD之前,人眼的玻璃体只能耐受一定程度的联结,这可能与玻璃体不稳定有关。
A quantitative study of synchysis senilis of vitreous and a statistical evaluation of its relationship to posterior vitreous detachment (PVD) was performed in eyes of 2,246 autopsied subjects (4,492 eyes); cases in which there was any cause for synchysis or PVD except senescence were excluded. Synchysis was graded 0 through 6 according to degree of destruction as judged by the technique of suspension-in-air; synchysis increased with age (P< 0.00005). PVD was also age-related, becoming notable in the seventh decade (27%) and reached a zenith in the eighth (63%). When the rate of PVD for each grade of synchysis was plotted, there was a significant upturn between synchysis grades 3 (50% destruction) and 4 (67%)(P< 0.00005); this trend was also evident when age was considered. These quantitative data reaffirm the role of synchysis in rhegmatogenous PVD and suggest that the vitreous of human eye can tolerate only a given degree of synchysis before some event, possibly related to vitreous instability, initiates PVD.