Extranodal NK/T cell lymphoma, nasal type.
Extranodal NK/T cell lymphoma, nasal type.
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DOI：
10.1684/ejd.2008.0504
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发表时间：
2008-08
期刊：
影响因子：
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通讯作者：
I. Zindancı;C. Demirkesen;M. Kavala;M. Koç;E. Kocaturk;S. Sudogan;B. Can
中科院分区：
文献类型：
--
作者：
I. Zindancı;C. Demirkesen;M. Kavala;M. Koç;E. Kocaturk;S. Sudogan;B. Can
结外自然杀伤（NK）/T细胞淋巴瘤（ENKL）是一种与EB病毒（EBV）感染密切相关的独特疾病实体。这种疾病在亚洲和中美洲和南美洲较为常见，但在北美和欧洲较为罕见。在病理学上，ENKL涉及可变大小淋巴细胞的多形性浸润，伴有炎症和坏死。恶性细胞表达胞浆CD 3和CD 56。EBV通过EBV编码的小RNA（EBER）原位杂交检测。
Extranodal natural killer (NK)/T-cell lymphoma (ENKL) is a unique disease entity that is strongly associated with Epstein–Barr virus (EBV) infection. This disease is more common in Asia and Central and South America but is rare in North America and Europe. Pathologically, ENKL involves polymorphous infiltration of variable-size lymphocytes with accompanying inflammation and necrosis. The malignant cells express cytoplasmic CD3 and CD56. EBV is detected by EBV-encoded small RNA (EBER) in situ hybridization.