Central Pontine Myelinolysis: A Clinical Reappraisal

Central Pontine Myelinolysis: A Clinical Reappraisal
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桥脑中央髓鞘溶解症：临床重新评估

DOI：
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发表时间：
1977
期刊：
影响因子：
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通讯作者：
V. S. Rossiter
V. S. Rossiter
中科院分区：
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文献类型：
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作者：
W. Wiederholt;Ronald M. Kobayashi;J. Stockard;V. S. Rossiter

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我们讨论了三例脑桥中央髓鞘溶解症（CPM）的临床表现。两名患者存活，神经功能缺损轻微，一名患者在神经功能缺损恢复期间死于医疗并发症。尸检显示典型的CPM病变。脑干听觉诱发电位的研究表明，在我们的两个病人有听觉桥脑通路的功能障碍，恢复正常的病人临床改善。我们的结论是CPM可以在临床上诊断，如果并发疾病得到积极治疗，患者可能会康复。
• We discuss three patients with clinical findings of central pontine myelinolysis (CPM). Two patients survived with minimal neurological deficits, and one patient died from medical complications while recovering from his neurological deficit. Postmortem examination showed the typical lesion of CPM. Brain stem auditory evoked potential studies in two of our patients indicate that there was impairment of function in auditory pontine pathways that returned to normal as the patients improved clinically. We conclude that CPM can be diagnosed clinically and that patients may recover if intercurrent illnesses are vigorously treated.