Effect of acute renal failure requiring renal replacement therapy on outcome in critically ill patients
Effect of acute renal failure requiring renal replacement therapy on outcome in critically ill patients
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DOI：
10.1097/00003246-200209000-00016
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发表时间：
2002-09-01
影响因子：
8.8
通讯作者：
Druml, W
中科院分区：
文献类型：
--
作者：
Metnitz, PGH;Krenn, CG;Druml, W
目标。急性肾衰竭是危重患者的一种并发症，与住院死亡风险过高有关。这是否反映了疾病的严重程度，或者急性肾功能衰竭是否是一个独立的危险因素尚不清楚。本研究的目的是分析奥地利重症监护病房中一组需要肾脏替代治疗的急性肾衰竭危重患者的疾病严重程度和死亡率。前瞻性、多中心队列研究。病人和环境。在2年的时间里，共有17,126名患者连续入住奥地利30个内科、外科和混合重症监护病房。测量和主要结果。分析的数据包括…任务数据、简化急性生理评分、Logistic器官功能障碍系统、简化治疗干预评分系统、重症监护病房住院时间、重症监护病房死亡率、住院死亡率。入院患者中，4.9% （n = 839）因急性肾功能衰竭（肾替代治疗患者）而接受肾替代治疗。这些病人。有更高的医院死亡率(62.8% vs. 15.6%, p
Objectives. Acute renal failure is a complication in critically 011 patients that has been associated with an excess risk of hospital mortality. Whether this reflects the severity of the disease or whether acute renal failure is an independent risk factor is unknown. The aim of this study was to analyze severity of illness and mortality in a group of critically ill patients with acute renal failure requiring renal replacement therapy in a number of Austrian intensive care units.Design. Prospective, multicenter cohort study.Patients and Setting. A total of 17,126 patients admitted consecutively to 30 medical, surgical, and mixed intensive care units in Austria over a period of 2 yrs.Measurements and Main Results. Analyzed data included ad.. mission data, Simplified Acute Physiology Score, Logistic Organ Dysfunction system, Simplified Therapeutic Intervention Scoring System, length of intensive care unit stay, intensive care unit mortality, and hospital mortality. Of the admitted patients, 4.9% (n = 839) underwent renal replacement therapy because of acute renal failure (renal replacement therapy patients). These patients. had a significantly higher hospital mortality (62.8% vs. 15.6%, p