Circadian variations of serum thyrotropin levels in man.
Circadian variations of serum thyrotropin levels in man.
复制标题
人类血清促甲状腺素水平的昼夜变化。
DOI：
10.1210/jcem-35-3-479
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发表时间：
1972
期刊：
影响因子：
--
通讯作者：
J. Golstein
中科院分区：
文献类型：
--
作者：
L. Vanhaelst;E. Cauter;J. Degaute;J. Golstein
本文研究了8例正常人血清促甲状腺激素（TSH）水平的昼夜变化。数据的分析表明存在2种不同的可再现现象，昼夜节律的特征在于重要的顶相和较低振幅较高频率的变化，周期在1和3小时之间。研究表明，神经机制是高频变化和昼夜节律现象的起源，后者与睡眠-觉醒周期有关。一个显着的差异，夜间和白天的平均TSH水平，观察女性，但在男性中没有。
ABSTRACT The existence of circadian variations in serum TSH levels was investigated in 8 normal subjects. The analysis of the data indicated the presence of 2 different reproducible phenomena, a circadian rhythm characterized by an important acrophase and lower amplitude higher frequency variations, with period between 1 and 3 hours. It is suggested that neural mechanisms are at the origin of both the high frequency variations and the circadian phenomenon, this latter being related to the sleep-wake cycle. A significant difference, between nocturnal and diurnal mean TSH levels was observed in women, but not in men.