Associations of Midlife to Late Life Fatigue With Physical Performance and Strength in Early Old Age: Results From a British Prospective Cohort Study
Associations of Midlife to Late Life Fatigue With Physical Performance and Strength in Early Old Age: Results From a British Prospective Cohort Study
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DOI：
10.1097/psy.0000000000000214
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发表时间：
2015-09-01
影响因子：
3.3
通讯作者：
Cooper, Rachel
中科院分区：
文献类型：
--
作者：
Manty, Minna;Kuh, Diana;Cooper, Rachel
ObjectivesTo研究协会的疲劳在中年和晚年的身体表现和力量在老年早期。MethodsData约1800名男性和女性从英国医学研究理事会全国健康与发展调查的数据疲劳在43岁和60至64岁。疲劳被定义为感觉疲劳，并在43岁和60至64岁时进行前瞻性评估。在这两个年龄段，参与者被归类为没有，偶尔或经常疲劳。身体性能和力量在60至64岁，使用四个客观的措施：握力，站立平衡，椅子上升，定时起床去（TUG）tests.ResultsThere之间的关联报告频繁疲劳在这两个年龄段和较差的握力，椅子上升，和TUG性能在60至64岁。此外，在这两个年龄段经常感到疲劳的人，（β = -4.09 kg，95%置信区间[CI] = -6.71至-1.48）和缓慢的椅子上升（β = -4.65次/min，95% CI = -6.65至-2.64）和TUG（β = -4.22 cm/s，95% CI = -12.16至-2.28）速度。这些协会是强大的，并保持调整后的一系列的协变量，包括体力活动和健康状况。ConclusionsReports的频繁疲劳与不良的身体表现在老年早期，特别是如果持续从中年到晚年。这些发现表明，不仅仅是疲劳，而是成年后持续的疲劳对以后的生活功能有影响。
ObjectivesTo examine associations of fatigue in midlife and later life with physical performance and strength in early old age.MethodsData on approximately 1800 men and women from the UK Medical Research Council National Survey of Health and Development with data on fatigue at ages 43 and 60 to 64 years were used. Fatigue was defined as perceived tiredness and was assessed prospectively at ages 43 and 60 to 64 years. At both ages, participants were categorized as having no, occasional, or frequent fatigue. Physical performance and strength were measured at age 60 to 64 years using four objective measures: grip strength, standing balance, chair rising, and timed get-up-and-go (TUG) tests.ResultsThere were associations between reports of frequent fatigue at both ages and poorer grip strength, chair rise, and TUG performance at 60 to 64 years. Furthermore, individuals reporting frequent fatigue at both ages had weaker grip strength (beta = -4.09 kg, 95% confidence interval [CI] = -6.71 to -1.48) and slower chair rise (beta = -4.65 repetitions/min, 95% CI = -6.65 to -2.64) and TUG (beta = -4.22 cm/s, 95% CI = -12.16 to -2.28) speeds when compared with those who reported no fatigue at both time points. These associations were robust and were maintained after adjustment for a range of covariates including physical activity and health status.ConclusionsReports of frequent fatigue were associated with poorer physical performance in early old age, especially if sustained from midlife to later life. These findings indicate that it is not just fatigue but fatigue sustained across adulthood that has implications for later life functioning.