Weight loss in obese patients with type 2 diabetes: Effects of telemonitoring plus a diet combination - The Active Body Control (ABC) Program
Weight loss in obese patients with type 2 diabetes: Effects of telemonitoring plus a diet combination - The Active Body Control (ABC) Program
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DOI：
10.1016/j.diabres.2010.11.020
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发表时间：
2011-03-01
影响因子：
5.1
通讯作者：
Westphal, Sabine
中科院分区：
文献类型：
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作者：
Luley, Claus;Blaik, Alexandra;Westphal, Sabine
目的：我们评估“主动身体控制(ABC)计划”对2型糖尿病患者的减肥效果。方法：ABC计划结合了对体力活动的远程监测和低热量饮食，同时也偏爱低血糖指数的碳水化合物。在这项为期6个月的随机临床试验中，35例患者(年龄57+/-9岁，BMI=35.3+/-5.7 kg/m(2))按ABC方案治疗，35例对照组(58+/-7岁，BMI=34.8+/-5.9 kg/m(2))接受标准治疗。结果：6个月后干预组平均体重减轻11.8 kg/-8.0 kg。血糖和糖化血红蛋白分别降低1.0mmo1/L和0.8%(p=0.000)。HbA1c>；7%的患者比例从57%下降到26%。13名患者(39%)停用抗糖尿病药物，14名患者(42%)减少用药。在6个月内，每个患者的药物成本降低了83。结论：ABC方案能有效降低2型糖尿病患者的体重、糖化血红蛋白和降糖药物的使用。(C)2010爱思唯尔爱尔兰有限公司。保留所有权利。
Aims: We evaluate the efficacy of the "Active Body Control (ABC) Program'' for weight reduction in patients with type 2 diabetes.Methods: The ABC program combines telemonitoring of the physical activity with a low-calorie diet also preferring carbohydrates with low glycemic indexes. In this 6-month, randomized, clinical trial 35 patients (aged 57 +/- 9 years; BMI = 35.3 +/- 5.7 kg/m(2)) were treated according to the ABC program and 35 control patients (aged 58 +/- 7 years; BMI = 34.8 +/- 5.9 kg/m(2)) received standard therapy.Results: After 6 months the mean weight loss in the intervention group was 11.8 kg +/- 8.0 kg. Glucose and HbA1c were lowered by respectively 1.0 mmol/l and 0.8 percentage points (p = 0.000, respectively). The proportion of patients with HbA1c > 7% fell from 57% to 26%. Antidiabetic drugs were discontinued in 13 patients (39%) and reduced in 14 (42%). The reduction of costs on medication per patient was (sic)83 in 6 months. In the control group, there were no relevant changes in body weight, laboratory values or drug treatment.Conclusions: The ABC program effectively lowers body weight, Hb1Ac and antidiabetic drug use in patients with type 2 diabetes. (C) 2010 Elsevier Ireland Ltd. All rights reserved.