Phenolic Derivatives from the Root Bark of Oplopanax horridus.
Phenolic Derivatives from the Root Bark of Oplopanax horridus.
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刺五加根皮的酚类衍生物
DOI：
10.1002/hlca.201300439
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发表时间：
2015-02
影响因子：
1.8
通讯作者：
Li SP
中科院分区：
文献类型：
--
作者：
Huang WH;Zhang QW;Wang CZ;Yuan CS;Li SP
从刺人参（Oplopanax horridus）根皮中分得4个新的酚类化合物，包括2个苯丙素苷、1个苯甲酸酯苷和1个木脂素苷，以及1个已知的甘油酯。新化合物的结构鉴定为3-{4-[（6-O-乙酰基-β-D-吡喃葡萄糖基）氧基]-3，5-二甲氧基苯丙酸（1），（+）-[5，6，7，8-四氢-7-（羟甲基）-10，11-二甲氧基二苯并[a，c][8]轮烯-6-基]甲基β-D-吡喃葡萄糖苷（2），（+）-甲基4-[6-O-{3-羟基-3-甲基-5-（1-甲基丙基）氧基]-5-氧代戊酰基}-4-O-（β-D-吡喃葡萄糖基）-β-D-吡喃葡萄糖基）氧基]-3-甲氧基苯甲酸酯（3），和2-甲氧基-4-[（1 E）-3-甲氧基-3-氧代丙-1-烯-1-基]苯基6-O-{3-羟基-3-甲基-5-[（1-甲基丙基）氧基]-5-氧代戊酰基-4-O-β-D-吡喃葡萄糖基-β-D-吡喃葡萄糖苷（4）。通过与文献报道的理化性质和光谱数据的比较，确定该化合物为阿魏酸甘油酯（5）。
Four new phenolic derivatives, including two phenylpropanoid glycosides, one benzoate glycoside, and one lignan glycoside, together with one known glyceride, were isolated from the root bark of Oplopanax horridus. The structures of the new compounds were elucidated as 3-{4-[(6-O-acetyl-β-D-glucopyranosyl) oxy]-3,5-dimethoxyphenylpropanoic acid (1), (+)-[5,6,7,8-tetrahydro-7- (hydroxylmethyl)-10,11-dimehoxydibenzo[a,c][8]annulen-6-yl]methyl β-D-glucopyranoside (2), (+)-methyl 4-[6-O-{3-hydroxy-3-methyl-5-(1-methylpropyl)oxy]-5-oxopentanoyl}-4-O-(β-D-glucopyranosyl)-β-D-glucopyranosyl)oxy]-3-methoxybenzoate (3), and 2-methoxy-4-[(1E)-3-methoxy-3-oxoprop-1-en-1-yl]phenyl 6-O-{3-hydroxy-3-methyl-5-[(1-methylpropyl)oxy]-5-oxopentanoyl-4-O-β-D-glucopyranosyl-β-D-glucopyranoside (4) on the basis of spectroscopic techniques including NMR and MS analyses. The known compound was identified as glycer-2-yl ferulate (5) by comparing its physical and spectral data with those reported in the literature.