Efficient fabrication of substrates for surface-assisted laser desorption/ionization mass spectrometry using laser ablation in liquids
Efficient fabrication of substrates for surface-assisted laser desorption/ionization mass spectrometry using laser ablation in liquids
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DOI：
10.1016/j.apsusc.2010.08.128
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发表时间：
2011
影响因子：
6.7
通讯作者：
T. Tsuji;Takeshi Mizuki;Masato Yasutomo;M. Tsuji;H. Kawasaki;T. Yonezawa;F. Mafuné
中科院分区：
文献类型：
--
作者：
T. Tsuji;Takeshi Mizuki;Masato Yasutomo;M. Tsuji;H. Kawasaki;T. Yonezawa;F. Mafuné
将激光烧蚀产生的金纳米颗粒在液体中电泳制备表面辅助激光解吸电离（SALDI）技术的底物。在整个制备过程中，没有添加任何辅助试剂来稳定和沉积纳米颗粒。电泳法制备的纳米颗粒比滴入法制备的纳米颗粒更均匀。结果表明，纳米颗粒沉积的均匀性提高了SALDI测量的重复性。此外，沉积的纳米颗粒的厚度影响SALDI效率。
Substrates for the surface-assisted laser desorption ionization (SALDI) technique were prepared using electrophoresis of gold nanoparticles produced by laser ablation in liquids. Throughout the preparation, no supplemental reagent was added for the stabilization and deposition of nanoparticles. Nanoparticles were deposited more uniformly using the electrophoresis technique than using dropping of the solution. Results demonstrated that the higher uniformity of the deposition of nanoparticles improved the reproducibility of SALDI measurements. Furthermore, the thickness of the deposited nanoparticles influences the SALDI efficiency.