Heritability: the link between development and the microevolution of molar tooth form
Heritability: the link between development and the microevolution of molar tooth form
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遗传性：臼齿形态发育与微观进化之间的联系
DOI：
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发表时间：
2018
期刊：
影响因子：
--
通讯作者：
O. Mock
中科院分区：
文献类型：
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作者：
P. D. Polly;O. Mock
摘要哺乳动物磨牙发育基因表达、形态发生和群体变异的研究日益深入，为综合进化和发育遗传学提供了一个模型系统。在这项研究中，我们用亲子回归的方法估计了最小的树懒隐子的摩尔形状(G)的加性遗传协方差。结果表明，树冠形状的H_2值为0.34(±0.08)，磨牙尖的遗传力高于齿尖。我们将遗传协方差与表型协方差(P)和环境协方差(E)进行了比较，并与釉质结发育级联(D)所期望的冠部特征的协方差进行了比较。我们发现G和D没有很强的相关性，G(阻力最小的进化线)的主轴比D更能预测高粱的进化差异。我们得出结论，釉质结级联确实对磨牙形状的进化施加了限制，但它是如此的宽容，以至于高粱之间的差异(其最后共同的祖先生活在大约1400万年前)并没有充分探索它的界限。在数千万年后，G将比D更好地预测摩尔形状的演化主轴。
Abstract The developmental gene expression, morphogenesis, and population variation in mammalian molar teeth has become increasingly well understood, providing a model system for synthesizing evolution and developmental genetics. In this study, we estimated additive genetic covariances in molar shape (G) using parent-offspring regression in Cryptotis parva, the Least Shrew. We found that crown shape had an overall h2 value of 0.34 (±0.08), with higher heritabilities in molar cusps than notches. We compared the genetic covariances to phenotypic (P) and environmental (E) covariances, and to the covariances in crown features expected from the enamel knot developmental cascade (D). We found that G and D were not strongly correlated and that major axes of G (evolutionary lines of least resistance) are better predictors of evolutionary divergences in soricines than is D. We conclude that the enamel knot cascade does impose constraints on the evolution of molar shape, but that it is so permissive that the divergences among soricines (whose last common ancestor lived about 14 million years ago) do not fully explore its confines. Over tens of millions of years, G will be a better predictor of the major axes of evolution in molar shape than D.
DOI：
10.1387/ijdb.7848830
发表时间：
1994-09
期刊：
The International journal of developmental biology
影响因子：
--
作者：
J. Jernvall;P. Kettunen;I. Karavanova;L. Martin;Irma Thesleff
通讯作者：
J. Jernvall;P. Kettunen;I. Karavanova;L. Martin;Irma Thesleff
影响因子：
3.3
作者：
D. Houle
通讯作者：
D. Houle