A ubiquitous tire rubber-derived chemical induces acute mortality in coho salmon
A ubiquitous tire rubber-derived chemical induces acute mortality in coho salmon
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DOI：
10.1126/science.abd6951
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发表时间：
2021-01-08
期刊：
影响因子：
56.9
通讯作者：
Kolodziej, Edward P.
中科院分区：
文献类型：
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作者：
Tian, Zhenyu;Zhao, Haoqi;Kolodziej, Edward P.
对于美国西北太平洋银鲑鱼（Oncorhynchus kisutch）来说，当成年鲑鱼迁徙到城市小溪繁殖时，每年都会暴露在雨水中，导致无法解释的急性死亡。通过研究这种现象，我们鉴定了N-（1，3-二甲基丁基）-N '-苯基-对苯二胺（6PPD）的高毒性醌转化产物，6PPD是全球普遍存在的轮胎橡胶抗氧化剂。对美国西海岸有代表性的道路径流和受雨水影响的小溪的回顾性分析表明，6PPD-醌（
In U.S. Pacific Northwest coho salmon (Oncorhynchus kisutch), stormwater exposure annually causes unexplained acute mortality when adult salmon migrate to urban creeks to reproduce. By investigating this phenomenon, we identified a highly toxic quinone transformation product of N-(1,3-dimethylbutyl)-N'-phenyl-p-phenylenediamine (6PPD), a globally ubiquitous tire rubber antioxidant. Retrospective analysis of representative roadway runoff and stormwater-affected creeks of the U.S. West Coast indicated widespread occurrence of 6PPD-quinone (