A Prospective Study of Arsenic Exposure From Drinking Water and Incidence of Skin Lesions in Bangladesh
A Prospective Study of Arsenic Exposure From Drinking Water and Incidence of Skin Lesions in Bangladesh
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DOI：
10.1093/aje/kwr062
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发表时间：
2011-07-15
影响因子：
5
通讯作者：
Ahsan, Habibul
中科院分区：
文献类型：
--
作者：
Argos, Maria;Kalra, Tara;Ahsan, Habibul
地下水中砷浓度的升高对全世界数百万人的公共健康构成威胁。作者旨在评估砷对健康影响纵向研究（HEALS）参与者中砷暴露与皮肤病变发生率之间的关联。该分析使用了10，182名基线无皮肤病变的成年人的数据，直到该队列的第三个两年期随访（2000-2009）。离散时间风险回归模型用于估计皮肤病变的风险比和95%置信区间。将10.1-50.0、50.1-100.0、100.1-200.0和>= 200.1 μ g/L与
Elevated concentrations of arsenic in groundwater pose a public health threat to millions of people worldwide. The authors aimed to evaluate the association between arsenic exposure and skin lesion incidence among participants in the Health Effects of Arsenic Longitudinal Study (HEALS). The analyses used data on 10,182 adults free of skin lesions at baseline through the third biennial follow-up of the cohort (2000-2009). Discrete-time hazard regression models were used to estimate hazard ratios and 95% confidence intervals for incident skin lesions. Multivariate-adjusted hazard ratios for incident skin lesions comparing 10.1-50.0, 50.1-100.0, 100.1-200.0, and >= 200.1 mu g/L with