Long-term outcome of isolated coronary artery bypass surgery in patients with severe left ventricular dysfunction
Long-term outcome of isolated coronary artery bypass surgery in patients with severe left ventricular dysfunction
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DOI：
10.1161/01.cir.0000128345.69540.ed
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发表时间：
2004-09-14
期刊：
影响因子：
37.8
通讯作者：
Ghali, WA
中科院分区：
文献类型：
--
作者：
Appoo, J;Norris, C;Ghali, WA
背景：冠状动脉旁路移植术（CABG）适用于冠状动脉疾病和心室功能受损的患者。然而，早期研究表明严重左心室功能不全患者预后极差。我们使用APPROACH注册表对这一高危患者群体与冠脉搭桥相关的预后进行了当代估计。方法与结果：研究对象为1996年至2001年加拿大阿尔伯塔省7841例孤立性冠脉搭桥患者。左心室功能明显降低（射血分数[EF] 50%， [NI] EF正常，n = 48 30）。Lo EF患者组的手术死亡率（4.6%）高于Med EF和N1 EF组（分别为3.4%和1.9%）
Background-Coronary artery bypass grafting (CABG) is indicated in patients with coronary artery disease and impaired ventricular function. However, earlier studies have suggested that prognosis of patients with severe left ventricular dysfunction is extremely poor. We used the APPROACH registry to derive contemporary estimates of prognosis associated with CABG for this high-risk patient population.Methods and Results-The study group consisted of 7841 patients who had isolated CABG in the province of Alberta, Canada between 1996 and 2001. Patients with markedly reduced left ventricular function (ejection fraction [EF] 50%, normal [NI] EF, n = 48 30). The operative mortality was higher in the patient group with Lo EF (4.6%) compared with Med EF and N1 EF groups (3.4% and 1.9%, respectively, P