Prevalence of hypertension at high altitude: cross-sectional survey in Ladakh, Northern India 2007-2011.
Prevalence of hypertension at high altitude: cross-sectional survey in Ladakh, Northern India 2007-2011.
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DOI：
10.1136/bmjopen-2014-007026
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发表时间：
2015-04-20
期刊：
影响因子：
2.9
通讯作者：
Okumiya K
中科院分区：
文献类型：
--
作者：
Norboo T;Stobdan T;Tsering N;Angchuk N;Tsering P;Ahmed I;Chorol T;Kumar Sharma V;Reddy P;Singh SB;Kimura Y;Sakamoto R;Fukutomi E;Ishikawa M;Suwa K;Kosaka Y;Nose M;Yamaguchi T;Tsukihara T;Matsubayashi K;Otsuka K;Okumiya K
高血压的患病率进行了检查，在一个广泛分散的（45 - 110平方公里）代表组的拉达克在北方印度。本文研究了大范围海拔（2600-4900 m）低氧环境及生活方式改变对高血压的影响。招募了2800名参与者（年龄20-94岁）。收缩压≥140 mm Hg和/或舒张压≥90 mm Hg和/或正在服用降压药定义为高血压。 检查身高、体重、体重指数和SpO 2。农村人口由六个分区组成，具有不同的海拔高度、饮食和职业模式。莱赫的参与者包括两个群体，即定居在莱赫的来自昌唐游牧地区的移民和出生在莱赫的居民。比较两组人群与农村农牧民高血压患病率。采用多因素Logistic回归分析了老龄化、缺氧、高海拔地区居住、肥胖、现代化职业、居住在城市和农村向城市迁移对高血压的影响。高血压患病率为37.0%，在所有参与者和定居在莱赫的移民（48.3%），其次是出生在莱赫的居民（41.1%），与那些在农村地区（33.5%）。居住在海拔较高地区（4000-4900 m）的游牧民族高血压患病率相对较低（全部：27.7%，藏族/拉达克族：19.7/31.9%）。 与高血压相关的因素是年龄、超重、居住在高海拔地区、从事现代化的久坐职业、居住在城市地区和从农村到城市的迁移。调整混杂因素后的多变量分析显示，生活方式改变和居住在高海拔地区与高血压独立相关。社会经济和文化因素在拉达克高原人高血压患病率中起着重要作用。
Prevalence of hypertension was examined in a widely dispersed (45 110 km2) representative group of Ladakhi in Northern India. The influence of hypoxic environment of wide-ranged altitude (2600–4900 m) and lifestyle change on hypertension was studied. 2800 participants (age 20–94 years) were enrolled. Systolic blood pressure ≥140 mm Hg and/or diastolic blood pressure of ≥90 mm Hg and/or taking current anti-hypertensive medicine was defined as hypertension. Height and weight for body mass index and SpO2 were examined. The rural population comprised six subdivisions with a distinct altitude, dietary and occupational pattern. Participants in the urban area of Leh consist of two groups, that is, migrants settled in Leh from the Changthang nomadic area, and dwellers born in Leh. The prevalence of hypertension in the two groups was compared with that in the farmers and nomads in rural areas. The effects of ageing, hypoxia, dwelling at high altitude, obesity, modernised occupation, dwelling in an urban area, and rural-to-urban migration to hypertension were analysed by multiple logistic regression. The prevalence of hypertension was 37.0% in all participants and highest in migrants settled in Leh (48.3%), followed by dwellers born in Leh town (41.1%) compared with those in rural areas (33.5). The prevalence of hypertension in nomads (all: 27.7%, Tibetan/Ladakhi: 19.7/31.9%)) living at higher altitude (4000–4900 m) was relatively low. The associated factors with hypertension were ageing, overweight, dwelling at higher altitude, engagement in modernised sedentary occupations, dwelling in urban areas, and rural-to-urban migration. The effects of lifestyle change and dwelling at high altitude were independently associated with hypertension by multivariate analysis adjusted with confounding factors. Socioeconomic and cultural factors play a big role with the effect of high altitude itself on high prevalence of hypertension in highlanders in Ladakh.
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影响因子：
39.3
作者：
Parati, Gianfranco;Bilo, Grzegorz;Mancia, Giuseppe
通讯作者：
Mancia, Giuseppe
DOI：
10.1073/pnas.1002443107
发表时间：
2010-06-22
影响因子：
11.1
作者：
Beall, Cynthia M.;Cavalleri, Gianpiero L.;Zheng, Yong Tang
通讯作者：
Zheng, Yong Tang
影响因子：
37.8
作者：
Levine, BD;Zuckerman, JH;deFilippi, CR
通讯作者：
deFilippi, CR
影响因子：
2.1
作者：
Sherpa, Lhamo Y.;Deji;Bjertness, Espen
通讯作者：
Bjertness, Espen
影响因子：
8.3
作者：
SOMERS, VK;MARK, AL;ABBOUD, FM
通讯作者：
ABBOUD, FM