Global burden of trauma: Need for effective fracture therapies.

Global burden of trauma: Need for effective fracture therapies.
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DOI:
10.4103/0019-5413.50843
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发表时间:
2009-04
影响因子:
1
通讯作者:
Hanson BP
Hanson BP
中科院分区:
医学4区
文献类型:
--
作者:
Mathew G;Hanson BP

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在过去的50年里,骨科创伤护理和骨折管理有了很大的进步。肌肉骨骼系统的生物学和生物力学、固定装置和软组织管理方面的新发展极大地影响了我们护理肌肉骨骼损伤的能力。许多疗法和治疗方式有可能通过减少侵入性操作和提供更短的愈合时间来改变未来的整形外科治疗。在实验模型中令人振奋的结果导致这些疗法在人类受试者中的临床应用增加。然而,对于许多方法,精确的临床适应症、时机、剂量和作用方式仍需明确。为了进一步制定骨折治疗策略,预测预后,改善新技术的临床应用,还需要进一步的研究。与不断发展的新疗法一起,改善骨折护理的战略应侧重于成本效益。这是全球整形外科社区与其他利益攸关方合作,解决发展中国家为肌肉骨骼损伤患者提供安全、及时和有效护理的许多障碍的绝佳机会。
Orthopedic trauma care and fracture management have advanced significantly over the last 50 years. New developments in the biology and biomechanics of the musculoskeletal system, fixation devices, and soft tissue management have greatly influenced our ability to care for musculoskeletal injuries. Many therapies and treatment modalities have the potential to transform future orthopedic treatment by decreasing invasive procedures and providing shorter healing times. Promising results in experimental models have led to an increase in clinical application of these therapies in human subjects. However, for many modalities, precise clinical indications, timing, dosage, and mode of action still need to be clearly defined. In order to further develop fracture management strategies, predict outcomes and improve clinical application of newer technologies, further research studies are needed. Together with evolving new therapies, the strategies to improve fracture care should focus on cost effectiveness. This is a great opportunity for the global orthopedic community, in association with other stakeholders, to address the many barriers to the delivery of safe, timely, and effective care for patients with musculoskeletal injuries in developing countries.
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