Seasonal occurrence of relapses in inflammatory myopathies: a preliminary study
Seasonal occurrence of relapses in inflammatory myopathies: a preliminary study
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DOI：
10.1007/s004150200036
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发表时间：
2002-04-01
影响因子：
6
通讯作者：
Mastaglia, FL
中科院分区：
文献类型：
--
作者：
Phillips, BA;Zilko, PJ;Mastaglia, FL
对53例皮肌炎(DM)或多发性肌炎(PM)患者的季节性复发进行了回顾性分析。在糖尿病组，肌炎和皮肤复发的发生率在夏季最高，而在PM组，复发在整个季节分布更均匀，但在夏季最低。目前的发现表明，环境因素，如并发感染和光照暴露，可能与重新激活疾病过程并导致DM复发有关，但在PM中则较少需要进一步的前瞻性研究来评估环境因素在炎症性肌病的启动和再激活中的作用。
The seasonal occurrence of relapses was analysed retrospectively in a group of 53 patients with treated dermatomyositis (DM) or polymyositis (PM). In DM, the incidence of both myositic and cutaneous relapses was highest in summer whereas in the PM group relapses was more evenly distributed throughout the seasons but lowest in summer. The present findings suggest that environmental factors such as intercurrent infections and light exposure maybe involved in reactivating the disease process and causing relapses in DM but less so in PM. Further prospective studies are needed to assess the role of environmental factors in the initiation and reactivation of the inflammatory myopathies.