Coronary artery calcifications in hemodialysis patients and their correlation with the prevalence of erectile dysfunction
Coronary artery calcifications in hemodialysis patients and their correlation with the prevalence of erectile dysfunction
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DOI：
10.1016/j.transproceed.2007.11.046
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发表时间：
2008-01-01
影响因子：
0.9
通讯作者：
Ergen, A.
中科院分区：
文献类型：
--
作者：
Inci, K.;Hazirolan, T.;Ergen, A.
导论.本研究的目的是调查血液透析患者中冠状动脉钙化评分（CACS）和勃起功能障碍（艾德）的患病率及其相关性。选择35例男性慢性肾功能衰竭患者参加本研究。所有患者均采用16通道多探测器计算机断层扫描进行CACS检查。通过计算自我管理的国际勃起功能指数（IIEF）的勃起功能域来确定艾德的存在和严重程度。患者年龄范围为22岁至78岁，平均年龄为51.6岁。血液透析的平均持续时间为75.7个月（范围= 12至232）。26例患者有一种或多种全身性疾病史。所有血液透析患者中任何水平的艾德的患病率为82.9%，重度艾德为40%。重度艾德患者的CACS显著更高（P = 0.032）。IIEF-5评分与CACS呈中度负相关（r = -.420，P =.012）。年龄、血液透析持续时间、体重指数、糖尿病、高血压、冠心病、高脂血症、甲状腺疾病、抑郁、吸烟和药物治疗与艾德的发生无关（P > 0.05）。艾德在血液透析患者中普遍存在。虽然许多可能的因素有助于艾德，艾德的严重程度随着CACS的增加而增加。
Introduction. Our aim in this study was to investigate the prevalence and correlation with coronary artery calcium scores (CACS) and erectile dysfunction (ED) among hemodialysis patients.Patients and methods. Thirty-five male patients with chronic renal failure were selected to participate in this study. All patients underwent examinations for CACS using 16-channel multidetector computed tomography. The presence and severity of ED were determined by calculating the erectile function domain of the self-administered International Index of Erectile Function (IIEF).Results. The patients' ages ranged from 22 to 78 with a mean of 51.6 years. The mean duration of hemodialysis was 75.7 months (range = 12 to 232). Twenty-six patients had a history of one or more systemic diseases. The prevalence of any level of ED was 82.9% for all hemodialysis patients, and severe ED, 40%. The CACS was significantly higher among patients with severe ED (P =.032). The IIEF-5 score was also shown to have a moderate negative correlation with the CACS (r = -.420, P =.012). Age, duration of hemodialysis, body mass index, diabetes mellitus, hypertension, coronary heart diseases, hyperlipidemia, thyroid disease, depression, tobacco consumption, and medication were not associated with the presence of ED (P >.05).Conclusion. ED is prevalent in hemodialysis patients. Although many possible factors contribute to ED, the severity of ED increases with greater CACS.