Factors Associated with Improved HIV/AIDS Treatment Outcomes: Comparing two Major ART Service Delivery Models in Vietnam
Factors Associated with Improved HIV/AIDS Treatment Outcomes: Comparing two Major ART Service Delivery Models in Vietnam
复制标题
与改善艾滋病毒/艾滋病治疗结果相关的因素：比较越南两种主要的抗逆转录病毒治疗服务提供模式
DOI：
10.1007/s10461-019-02571-z
复制
发表时间：
2019
影响因子：
4.4
通讯作者：
C. Latkin
中科院分区：
文献类型：
--
作者：
B. Tran;Q. N. Nguyen;L. H. Nguyen;C. Nguyen;H. Do;Nu Thi Truong;C. Latkin
采用混合设计方法，对362例接受抗逆转录病毒治疗的HIV患者（来自HIV检测和咨询（ART-HTC）服务诊所和普通医疗保健（ART-GH）服务诊所）的CD 4计数水平及其相关因素进行评估。纵向CD 4计数数据从病历中回顾性收集。社会人口学，临床，饮酒和吸烟的特点，通过面对面的采访。多元混合效应线性回归用于确定相关性。我们发现，与ART-HTC诊所的患者相比，ART-GH诊所的HIV患者更有可能随着时间的推移获得更高的CD 4计数。此外，发现CD 4计数增加与ART持续时间较长和基线CD 4水平较高相关。然而，吸烟和危险的酒精使用与CD 4计数的改善无关。我们的研究结果表明，HTC和GH服务相结合，可能会提供一个协同效益的ART治疗结果，通过改善获得全面的艾滋病毒医疗服务的艾滋病毒患者的治疗。
A mixed design approach was performed to assess the CD4 count levels over time and their associated factors among 362 HIV patients on ART from clinics with HIV testing and counseling (ART-HTC) services and those with general healthcare (ART-GH) services. Longitudinal CD4 count data were retrospectively collected from medical records. Sociodemographic, clinical, alcohol use and smoking characteristics were obtained via face-to-face interviews. Multivariate mixed effect linear regression was utilized to determine the association. We found that HIV patients at ART-GH clinics were more likely to achieve higher CD4 counts over time compared to patients at ART-HTC clinics. Additionally, having an increase in CD4 counts was found to be associated with having longer duration of ART and higher baseline CD4 levels. Cigarette smoking and hazardous alcohol use, however, were not associated with CD4 count improvement. Our findings suggest that combining HTC and GH services might provide a synergistic benefit in ART treatment outcomes through an improved access to comprehensive HIV healthcare services for HIV patients on therapy.
影响因子：
4.2
作者：
Collins LF;Clement ME;Stout JE
通讯作者：
Stout JE
使用横截面数据进行纵向推断的混合方法。
影响因子：
2.5
作者：
Aaronson,LS;Kingry,MJ
通讯作者：
Kingry,MJ