3D MPRAGE Evaluation of the Internal Auditory Canals
3D MPRAGE Evaluation of the Internal Auditory Canals
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内耳道的 3D MPRAGE 评估
DOI：
10.1097/00004728-199305000-00020
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发表时间：
1993
影响因子：
1.3
通讯作者：
M. Modic
中科院分区：
文献类型：
--
作者：
Manjuhl Shah;Jonathan J Ross;J. Tkach;M. Modic
利用 180° 反转脉冲的重 T1 加权三维 (3D) 梯度回波序列已可供临床使用，称为磁化准备快速采集梯度回波 (MPRAGE)。通过适当选择重复时间、回波时间、翻转角和反转时间 (T1)，可以执行具有出色解剖细节和良好信噪比的 T1 加权成像。与传统的自旋回波 (SE) 成像相比，我们对该序列进行了初步评估，以检测内耳道的异常情况。 15 名男性和 15 名女性接受了评估。诊断包括正常（n = 15 名患者）、听神经瘤（n = 4 名患者中的 7 个肿瘤）、小脑桥脑角脑膜瘤（n = 3）、听神经瘤术后无残留肿瘤（n = 2）、术后有残留肿瘤证据（n = 3）、颈静脉球（n = 1）、贝尔麻痹（n = 1）和可能病毒病因的前庭增强（n = 1）。 3D MPRAGE 研究包括 128 个冠状分区、(10/4/1)、10° 翻转角、130 ± 256 矩阵、2 mm 切片厚度、350 ms 的 TI 时间、1 s 恢复时间和 5.43 分钟检查时间。在传统 SE T1 加权成像上识别出的所有增强病灶也在 MPRAGE 成像上识别出来。当存在病理时，MPRAGE 和传统 SE 序列之间不存在诊断差异，但 MPRAGE 序列在与 130 256 面内矩阵相关的轴向重新格式化中确实具有较差的分辨率。虽然目前无法取代传统的二维 SE 成像，但 3D MPRAGE 可能为常规成像方案提供有价值的辅助。该技术可以取代冠状 T1− 加权 SE 序列，并提供出色的灰白色分化和许多连续的薄切片，而不会大幅增加总体检查时间。
A heavily T1-weighted three-dimensional (3D) gradient echo sequence utilizing a 180° inversion pulse has become available for clinical use, called magnetization prepared rapid acquisition gradient echo (MPRAGE). With the appropriate choice of repetition time, echo time, flip angle, and inversion time (T1), T1-weighted imaging can be performed with excellent anatomic detail and a good signal-to-noise ratio. We performed an initial evaluation of this sequence for detection of abnormalities of the internal auditory canals compared with conventional spin echo (SE) imaging. Fifteen men and 15 women were evaluated. Diagnoses included normal (n = 15 patients), acoustic neuromas (n = 7 tumors in 4 patients), cerebellopontine angle meningiomas (n = 3), postoperative for acoustic neuroma without residual tumor (n = 2), postoperative with evidence of residual tumor (n = 3), glomus jugulare (n = 1), Bell palsy (n = 1), and vestibular enhancement of probable viral etiology (n = 1). The 3D MPRAGE study consisted of 128 coronal partitions, (10/4/1), 10° flip angle, 130 ± 256 matrix, 2 mm slice thickness, TI time of 350 ms, 1 s recovery time, and 5.43 min examination time. All enhancing lesions identified on the conventional SE T1-weighted imaging were also identified on the MPRAGE imaging. No diagnostic difference existed between the MPRAGE and conventional SE sequences when pathology was present, but the MPRAGE sequence did have poorer resolution in the axial reformats related to the 130 256 in-plane matrix. While not currently able to replace conventional two-dimensional SE imaging, 3D MPRAGE may provide a valuable adjunct to the routine imaging protocol. This technique could replace the coronal T1− weighted SE sequence and provide excellent gray-white differentiation and many contiguous thin sections without a great increase in overall examination time.