Surgical treatment and outcome of conventional pelvic chondrosarcoma
Surgical treatment and outcome of conventional pelvic chondrosarcoma
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DOI：
10.1302/0301-620x.87b11.16621
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发表时间：
2005-11-01
影响因子：
--
通讯作者：
Mercuri, M
中科院分区：
文献类型：
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作者：
Donati, D;El Ghoneimy, A;Mercuri, M
我们回顾了124例传统的骨盆软骨肉瘤谁已经治疗了20年。我们记录了肿瘤的类型（中央或外周），手术类型（保肢手术或半骨盆切除术），肿瘤的分级，局部复发和/或转移，以确定可能影响生存的因素，更令人满意的手术边缘达到中央肿瘤或半骨盆切除术治疗的患者。然而，1级肿瘤，无论过程中，没有发展转移或导致死亡，而3级肿瘤有最差的结果和预后。中央，高级别的肿瘤需要积极的手术治疗，以达到足够的手术切缘，特别是在那些病变位于骶髂关节附近。相比之下，1级外周软骨肉瘤可以用污染的切缘治疗，以减少手术发病率，但不会降低生存率。
We reviewed 124 patients with a conventional pelvic chondrosarcoma who had been treated over a period of 20 years. We recorded the type of tumour (central or peripheral), type of operation (limb salvage surgery or hemipelvectomy), the grade of tumour, local recurrence and/or metastases, in order to identify the factors which might influence survival.More satisfactory surgical margins were achieved for central tumours or in those patients treated by hemipelvectomy. However, grade 1 tumours, whatever the course, did not develope metastases or cause death, while grade 3 tumours had the worst outcome and prognosis.Central, high-grade tumours require aggressive surgical treatment in order to achieve adequate surgical margins, particularly in those lesions located close to the sacroiliac joint. By contrast, grade 1 peripheral chondrosarcomas may be treated with contaminated margins in order to reduce operative morbidity, but without reducing survival.