EFFECTS OF STRESS AND PSYCHOTROPIC DRUGS ON RAT LIVER TRYPTOPHAN PYRROLASE.
EFFECTS OF STRESS AND PSYCHOTROPIC DRUGS ON RAT LIVER TRYPTOPHAN PYRROLASE.
复制标题
压力和精神药物对大鼠肝脏色氨酸吡咯酶的影响。
作者：
J. Nomura
应激和氯丙嗪使大鼠肝脏色氨酸吡啶酶活性显著升高。肾上腺切除术不能阻止氯丙嗪产生的酶活性的增加，但垂体切除术消除了酶的诱导。还研究了几种激素和精神药物的作用。提示垂体和肾上腺均参与大鼠肝脏色氨酸pyr的调节。rolase活动。(内分泌学76:1190,1965)
The activity of tryptophan pyrrolase in rat liver was significantly increased by stress and by chlorpromazine administration. Adrenalectomy did not prevent the increase in enzyme activity produced by chlorpromazine, but hypophysectomy eliminated the enzyme induction. The effect of several hormones and of psychotropic drugs was also studied. It was indicated that the pituitary as well as the adrenal was involved in the regulation of rat liver tryptophan pyr. rolase activity. (Endocrinology 76:1190,1965)