The morphology of collicular and retinal axons ending on small relay (W-like) cells of the primate lateral geniculate nucleus.
The morphology of collicular and retinal axons ending on small relay (W-like) cells of the primate lateral geniculate nucleus.
复制标题
终止于灵长类外侧膝状核的小中继（W 样）细胞的丘脑和视网膜轴突的形态。
DOI：
10.1017/s0952523800004648
复制
发表时间：
1993
影响因子：
1.9
通讯作者：
Casagrande,VA
中科院分区：
文献类型：
--
作者：
Lachica,EA;Casagrande,VA
每种灵长类动物的外侧膝状核(LGN)除了含有不同的大细胞和小细胞中继细胞外，还含有一组小的中继细胞。这些小细胞通过上丘接受直接的视网膜投射和间接的视网膜投射。对灌木状灵长类动物灌木幼体的小LGN细胞的感受野分析表明，该细胞类由亚类组成，在生理上与猫W细胞相似。为了确定其中的一些亚类，我们研究了丛生婴儿Galago crassicaudatus LGN中终止于小W样细胞的视网膜和胶状轴突的形态特征。该物种的小细胞位于一对突出的角细胞(K)层和板层间区(ILZ)。视网膜乔木被大量离子导入辣根过氧化物酶注射到视束中。通过离子导入将生物细胞素注入SC的浅层，填充结肠树枝。对48根轴突进行了完全重建和定量评价。我们的发现表明，视网膜和丘状轴突终末在许多标准的基础上在形态上有所不同。我们的分析还表明，视网膜轴突可能对K细胞有更强的影响，而丘状轴突对ILZ细胞有更强的影响。这些发现的结果具有挑衅性，因为已知这些小的LGN细胞直接投射到纹状皮质内的细胞色素氧化酶(CO)斑点。这种关系表明，CO斑点细胞不仅接受来自大细胞和小细胞LGN细胞的复杂视觉输入，还接受受视网膜细胞和丘状细胞影响的小细胞通路的复杂视觉输入。
The lateral geniculate nucleus (LGN) of every primate examined contains a set of small relay cells in addition to separate sets of magnocellular and parvocellular relay cells. These small cells receive a direct retinal projection, and an indirect retinal projection via the superior colliculus (SC). Receptive-field analyses of the small LGN cells in the bush baby, a lorisiform primate, indicate that this cell class is composed of subclasses, similar in physiology to cat W cells. In an effort to identify some of these subclasses, we have examined the morphological features of retinal and collicular axonal arbors that end on small W-like cells in the LGN of the bush baby, Galago crassicaudatus. Small cells in this species are found in a prominent pair of koniocellular (K) layers as well as the interlaminar zones (ILZs).Retinal arbors were examined by bulk iontophoretic injection of horseradish peroxidase into the optic tract. Collicular arbors were filled via iontophoretic injection of biocytin into the superficial layers of the SC. Forty-eight axon arbors were completely reconstructed and quantitatively evaluated. Our findings show that retinal and collicular axon terminals differ in morphology on the basis of a number of criteria. Our analyses also suggest that retinal axons may have a stronger influence on K cells and collicular axons have a stronger influence on ILZ cells. The ramifications of these findings are provocative since these small LGN cells are known to project directly to the cytochrome-oxidase (CO) blobs within striate cortex. This relationship suggests that CO blob cells receive complex visual input not only from magnocellular and parvocellular LGN cells, but also from small cell pathways that are differentially influenced by retinal and collicular cells.