Turning Participatory Microbiome Research into Usable Data: Lessons from the American Gut Project.
Turning Participatory Microbiome Research into Usable Data: Lessons from the American Gut Project.
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DOI：
10.1128/jmbe.v17i1.1034
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发表时间：
2016-03
影响因子：
1.9
通讯作者：
Knight R
中科院分区：
文献类型：
--
作者：
Debelius JW;Vázquez-Baeza Y;McDonald D;Xu Z;Wolfe E;Knight R
人类微生物组的作用是持续调查的主题，从而增加了理解。然而，目前的微生物组研究只触及了各种健康微生物组的表面。通过众包和众筹微生物组研究的公众参与为参与者和研究者提供了一个新的机会。然而，将参与性科学转化为可发表的数据可能具有挑战性。与参与者基础和研究人员之间的清晰沟通可以改善一些挑战。需要考虑三个主要方面：招募和持续的互动，样本收集和数据分析。通过勤勉的参与者互动、仔细的调查设计和维护开源管道，可用数据可以最大化。虽然参与式科学将补充而不是取代传统途径，但它为微生物组和其他领域的研究提供了新的机会。
The role of the human microbiome is the subject of continued investigation resulting in increased understanding. However, current microbiome research has only scratched the surface of the variety of healthy microbiomes. Public participation in science through crowdsourcing and crowdfunding microbiome research provides a novel opportunity for both participants and investigators. However, turning participatory science into publishable data can be challenging. Clear communication with the participant base and among researchers can ameliorate some challenges. Three major aspects need to be considered: recruitment and ongoing interaction, sample collection, and data analysis. Usable data can be maximized through diligent participant interaction, careful survey design, and maintaining an open source pipeline. While participatory science will complement rather than replace traditional avenues, it presents new opportunities for studies in the microbiome and beyond.