Adaptation and implementation of an evidence-based behavioral medicine program in diverse global settings: The Williams LifeSkills experience.
Adaptation and implementation of an evidence-based behavioral medicine program in diverse global settings: The Williams LifeSkills experience.
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在不同的全球环境中适应和实施循证行为医学计划：威廉姆斯生活技能经验。
DOI：
10.1007/s13142-011-0030-6
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发表时间：
2011
影响因子：
3.6
通讯作者：
Williams,VirginiaP
中科院分区：
文献类型：
--
作者：
Williams,RedfordB;Williams,VirginiaP
流行病学研究已经证明了敌意、抑郁、焦虑、工作压力、社会孤立和社会经济地位低下等心理社会因素对健康的损害作用。一些研究表明，行为干预可以降低这些心理社会因素的水平。在此，我们描述了转化过程，其中威廉姆斯LifeSkills®（WLS®）计划和产品，以减少心理社会风险因素已被开发和测试在美国和加拿大的临床试验，然后适应其他文化，并在临床试验中测试在世界各地的其他国家。在美国和其他地方发表的WLS®产品对照和观察性试验的证据表明，使用WLS®产品接受应对技能培训的人一直报告心理社会风险因素水平降低。在两项对照试验中，一项针对美国阿尔茨海默病亲属的护理人员，另一项针对新加坡冠状动脉搭桥手术患者，WLS®训练也产生了临床显著的血压降低。总之，WLS®产品已在对照和观察性试验中显示，可降低心理社会和心血管压力指数。正在进行的研究有可能表明，WLS®产品可以成为发展中国家提供减压和心理健康服务的有效工具。
Epidemiological research has documented the health-damaging effects of psychosocial factors like hostility, depression, anxiety, job stress, social isolation and low socioeconomic status. Several studies suggest that behavioral interventions can reduce levels of these psychosocial factors. Herein we describe the translational process whereby the Williams LifeSkills® (WLS®) program and products for reducing psychosocial risk factors have been developed and tested in clinical trials in the U.S. and Canada and then adapted for other cultures and tested in clinical trials in other countries around the world. Evidence from published controlled and observational trials of WLS®products in the U.S. and elsewhere shows that persons receiving coping skills training using WLS®products have consistently reported reduced levels of psychosocial risk factors. In two controlled trials, one for caregivers of a relative with Alzheimer's Disease in the U.S. and one for coronary bypass surgery patients in Singapore, WLS®training also produced clinically significant blood pressure reductions. In conclusion, WLS®products have been shown in controlled and observational trials to produce reduced levels of both psychosocial and cardiovascular stress indices. Ongoing research has the potential to show that WLS®products can be an effective vehicle for the delivery of stress reduction and mental health services in developing countries.