Surgeon Scientists Are Disproportionately Affected by Declining NIH Funding Rates
Surgeon Scientists Are Disproportionately Affected by Declining NIH Funding Rates
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DOI：
10.1016/j.jamcollsurg.2017.12.047
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发表时间：
2018-04-01
影响因子：
5.2
通讯作者：
Ailawadi, Gorav
中科院分区：
文献类型：
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作者：
Narahari, Adishesh K.;Mehaffey, J. Hunter;Ailawadi, Gorav
背景技术背景：在过去的10年里，由于研究赠款的数量减少和NIH申请数量的增加，获得NIH资助变得越来越困难。研究设计：使用来自NIH、美国实验生物学学会联合会（FASEB）、蓝岭医学院Blue Ridge Medical Institute接下来，使用美国国立卫生研究院研究组合在线报告工具支出和结果（NIH Reporter）确定了所有以外科医生为主要研究者的NIH赠款（2006年至2016年），并根据每笔资金的出版物影响因子计算了每笔赠款的赠款影响评分。结果：NIH基金申请数增加了18.7%（p = 0.0009），而赠款数（p < 0.0001）和R 01（p < 0.0001）分别减少了6.7%和17.0%。以外科医生为主要研究者的基金赠款的平均成功率（16.4%）显著低于NIH的平均资助率（19.2%）（p = 0.011）。尽管在此期间仅收到831份R 01，但外科医生科学家的工作效率很高，每10万美元的平均拨款影响得分为4.9，在过去10年中有所增加（0.15 +/- 0.05/年，p = 0.02）。此外，从2007年到2012年，外科医生科学家指导的K奖项转换为R 01 s的比例为46%。结论：尽管过去10年的资金不断减少，但外科医生科学家的生产力不断提高，这是通过有影响力的出版物和早期研究者奖项转换为R 01 s的更高成功率来衡量的。(C)2018年美国外科医生学会爱思唯尔公司出版All rights reserved.
BACKGROUND: Obtaining National Institutes of Health (NIH) funding over the last 10 years has become increasingly difficult due to a decrease in the number of research grants funded and an increase in the number of NIH applications.STUDY DESIGN: National Institutes of Health funding amounts and success rates were compared for all disciplines using data from NIH, Federation of American Societies for Experimental Biology (FASEB), and Blue Ridge Medical Institute. Next, all NIH grants (2006 to 2016) with surgeons as principal investigators were identified using the National Institutes of Health Research Portfolio Online Reporting Tools Expenditures and Results (NIH RePORTER), and a grant impact score was calculated for each grant based on the publication's impact factor per funding amount. Linear regression and one-way ANOVA were used for analysis.RESULTS: The number of NIH grant applications has increased by 18.7% (p = 0.0009), while the numbers of funded grants (p < 0.0001) and R01s (p < 0.0001) across the NIH have decreased by 6.7% and 17.0%, respectively. The mean success rate of funded grants with surgeons as principal investigators (16.4%) has been significantly lower than the mean NIH funding rate (19.2%) (p = 0.011). Despite receiving only 831 R01s during this time period, surgeon scientists were highly productive, with an average grant impact score of 4.9 per $100,000, which increased over the last 10 years (0.15 +/- 0.05/year, p = 0.02). Additionally, the rate of conversion of surgeon scientist-mentored K awards to R01s from 2007 to 2012 was 46%.CONCLUSIONS: Despite declining funding over the last 10 years, surgeon scientists have demonstrated increasing productivity as measured by impactful publications and higher success rates in converting early investigator awards to R01s. (C) 2018 by the American College of Surgeons. Published by Elsevier Inc. All rights reserved.