Fluid-structure interaction modeling of lactating breast: Newtonian vs. non-Newtonian milk
Fluid-structure interaction modeling of lactating breast: Newtonian vs. non-Newtonian milk
复制标题
哺乳期乳房的流固耦合模型：牛顿奶与非牛顿奶
DOI：
10.1016/j.jbiomech.2021.110500
复制
发表时间：
2021
影响因子：
2.4
通讯作者：
Hassanipour, Fatemeh
中科院分区：
文献类型：
--
作者：
Azarnoosh, Jamasp;Hassanipour, Fatemeh
母乳喂养是一个高度动态和复杂的机制。婴儿的哺乳过程包括压缩和口腔内真空压力，导致乳汁从乳房中流出。在哺乳周期中，乳头中累积的乳汁根据乳汁的性质和瞬时流率而变化。对原料人乳的流变学研究表明，牛奶具有非牛顿剪切稀化流动行为。本研究旨在通过流体-结构相互作用(FSI)模拟来研究非牛顿牛奶对乳腺导管系统流动行为的影响。给出了非牛顿效应对牛乳流速和体积流量的影响结果。结果表明，非牛顿Carreau模型在模拟母乳在乳腺导管系统中的流动时具有很好的应用前景。此外，研究结果还表明，在哺乳周期的30-35%的时间里，非牛顿效应对牛乳的流动行为产生了影响。因此，牛顿模型在数值模拟方面是可以接受的。
Breastfeeding is a highly dynamic and complex mechanism. The suckling process by the infant involves compression and intra-oral vacuum pressure, leading to milk expression from breast. The accumulated milk from the nipple varies depending on the milk properties and transient flow rate during the suckling cycle. Rheological studies on raw human milk indicate that milk has a non-Newtonian shear-thinning flow behavior. This study aims to investigate the effect of non-Newtonian milk on flow behavior through the breast ductal system using fluid–structure interaction (FSI) simulation. The results of the non-Newtonian effects on flow velocity and the volumetric flow rate of expressed milk are presented. The results show that non-Newtonian Carreau model is promising for the simulation of human milk flow through the breast ductal systems. Also, the results show that the non-Newtonian effects on the milk flow behavior appear for 30–35% of the suckling cycle. Therefore, the Newtonian model is acceptable for the purpose of numerical simulation.