NON-INVASIVE EVALUATION OF PULMONARY-HYPERTENSION BY A PULSED DOPPLER TECHNIQUE
NON-INVASIVE EVALUATION OF PULMONARY-HYPERTENSION BY A PULSED DOPPLER TECHNIQUE
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DOI：
10.1161/01.cir.68.2.302
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发表时间：
1983-01-01
期刊：
影响因子：
37.8
通讯作者：
ABE, H
中科院分区：
文献类型：
--
作者：
KITABATAKE, A;INOUE, M;ABE, H
应用脉冲多普勒技术检测33例成人右室流出道的血流频谱。在肺动脉压正常的患者中(平均压力<20 mm Hg，16例)，射血流量在收缩中期达到峰值(137±-)。24毫秒，平均+-。SD)，产生收缩时血流速度模式的圆顶状轮廓。相比之下，肺动脉高压患者的血流速度模式(平均压。20 mm Hg，17例患者)加速较快，达峰值时间较早(97.+-)。20ms，P<；0.01)；在10例肺动脉高压患者中，在减速过程中观察到继发性较慢的血流速度上升，导致收缩中期切迹。根据血流速度图测量血流达峰时间(加速时间，ACT)和右室射血时间(RVET)。ACT或ACT/RVET均随平均肺动脉压的升高而降低，且ACT/RVET与平均肺动脉压log10呈极显著负相关(r=-0.90)。这项技术的使用使得对肺动脉压力的无创估计成为可能。
A pulsed Doppler technique was used to examine the flow velocity pattern in the right ventricular outflow tract in 33 adults. In the patients with normal pulmonary artery pressure (mean pressure < 20 mm Hg, 16 patients), ejection flow reached a peak level at midsystole (137 .+-. 24 ms, mean .+-. SD), producing a dome-like contour of the flow velocity pattern during systole. In contrast, the flow velocity pattern in patients with pulmonary hypertension (mean pressure .gtoreq. 20 mm Hg, 17 patients) was demonstrated to accelerate rapidly and to reach a peak level sooner (97 .+-. 20 ms, P < 0.01); in 10 of the pulmonary hypertensive patients a secondary slower rise in flow velocity was observed during a deceleration, resulting in the midsystolic notching. The time to peak flow (acceleration time, AcT) and right ventricular ejection time (RVET) were measured from the flow velocity pattern. Either AcT or AcT/RVET decreased with increase in mean pulmonary artery pressure, and a very high correlation (r = -0.90) was found between AcT/RVET and log10 (mean pulmonary artery pressure). The use of this technique permitted the noninvasive estimation of the pulmonary artery pressure.