Processing speed and longitudinal trajectories of change for cognitive abilities: The Swedish Adoption/Twin Study of Aging
Processing speed and longitudinal trajectories of change for cognitive abilities: The Swedish Adoption/Twin Study of Aging
复制标题
DOI：
10.1080/13825580490511152
复制
发表时间：
2004-06-01
影响因子：
1.9
通讯作者：
Pedersen, NL
中科院分区：
文献类型：
--
作者：
Finkel, D;Pedersen, NL
在这份手稿中，瑞典收养/双胞胎衰老研究（SATSA）被描述。虽然这项研究是一个多学科的老年遗传学项目，但研究结果的总结主要集中在认知措施上。在论文的第二部分，我们研究了处理速度在解释认知能力变化的纵向轨迹以及遗传和环境对这些轨迹的影响方面所起的作用。当处理速度从代表三个认知领域（结晶、流体和记忆）和一般认知因素的认知测量中倒退时，下降的轨迹不那么严重。定量遗传分析表明，环境变异在成年后期增加。这些认知能力的遗传变异很大一部分是由速度的遗传变异造成的。随着年龄的增长，与处理速度相关的遗传变异成为流体能力和一般认知因素遗传变异的一个更突出的组成部分。
In this manuscript, The Swedish Adoption/Twin Study of Aging (SATSA) is described. Although the study is a multidisciplinary program in gerontological genetics, the summary of findings focuses on the cognitive measures. In the second part of the manuscript, we investigate the role played by measures of processing speed in explaining the longitudinal trajectories of change for cognitive abilities and the genetic and environmental influences on those trajectories. When processing speed was regressed out of cognitive measures representing three cognitive domains (crystallized, fluid, and memory) and a general cognitive factor, the trajectory of decline was less severe. Quantitative genetic analyses indicated that environmental variance increases in late adulthood. A substantial portion of the genetic variance for these cognitive abilities was accounted for by genetic variance for speed. With increasing age, genetic variance associated with processing speed becomes a more prominent component of genetic variance for fluid abilities and for the general cognitive factor.