Application of Magnetic Resonance Diffusion Tensor Imaging in the Clinical Diagnosis of Disc Herniation after Lumbar Spine Injury.

Application of Magnetic Resonance Diffusion Tensor Imaging in the Clinical Diagnosis of Disc Herniation after Lumbar Spine Injury.
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磁共振弥散张量成像在腰椎损伤后椎间盘突出症诊断中的应用。

DOI:
10.1155/2021/6610988
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发表时间:
2021
影响因子:
--
通讯作者:
Jin A
Jin A
中科院分区:
医学4区
文献类型:
--
作者:
Wu P;Huang C;Li W;Yuan A;Jin A

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磁共振弥散加权成像(DTI)对脊髓损伤过程中的病理生理和微结构变化提供了独特的视角,具有高度的空间特异性;同时,NM反映了神经电信号在脊髓纤维束中的传导和完整性,具有时间特异性和动态评估效果。各向异性分数(FA)值、SEP波幅和神经功能评分或改善率相关。DTI和NM相结合可以更可靠地量化脊髓功能,评估治疗效果,判断患者预后,为脊髓损伤患者的临床决策和未来研究提供参考。即术前FA值越低,SEP波幅越低,术前术后神经功能越差,改善率越低,预后越差。因此,我们认为可以根据JOA评分对脊髓功能进行分级,以找到相应的FA和SEP波幅范围,并且通过未来测量FA和SEP波幅,可以逆转对脊髓功能、术后预期改善和长期预后的评估。同时,FA值也在一定程度上有助于判断病变的性质。
Magnetic resonance diffusion-weighted imaging (DTI) provides a unique perspective on the pathophysiological and microstructural changes during spinal cord injury, with high spatial specificity; meanwhile, NM reflects the conduction and integrity of neuroelectrical signals in spinal cord fiber tracts, with time-specific and dynamic evaluation effects. The fractional anisotropy (FA) value, SEP amplitude, and neurological function score or improvement rate are correlated. The combination of DTI and NM can more reliably quantify the spinal cord function, evaluate the effectiveness of treatment, and determine the patient's prognosis, which can provide reference for clinical decision making and future research for SCI patients. That is, the lower the preoperative FA value and the lower the SEP amplitude, the worse the preoperative and postoperative neurological function, the lower the improvement rate, and the worse the prognosis of patients. Therefore, we believe that spinal cord function can be graded according to JOA scores to find the corresponding FA and SEP amplitude ranges and that, by measuring FA and SEP amplitude in the future, we can reverse the assessment of spinal cord function, expected postoperative improvement, and long-term prognosis. At the same time, FA values can also help determine the nature of the lesion to some extent.
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