Bioapplications of Magnetic Nanowires: Barcodes, Biocomposites, Heaters
Bioapplications of Magnetic Nanowires: Barcodes, Biocomposites, Heaters
复制标题
DOI：
10.1109/tmag.2022.3151608
复制
发表时间：
2022-08-01
影响因子：
2.1
通讯作者：
Stadler，Bethanie J. H.
中科院分区：
文献类型：
--
作者：
Kouhpanji，Mohammad Reza Zamani;Zhang，Yali;Stadler，Bethanie J. H.
磁性纳米线（MNW）可以通过几种机制使其磁矩反转，所述机制使用合成的阵列中的纳米线的组成、长度、直径和密度或作为测定或凝胶中的单个纳米颗粒来控制。这种磁反转的定制导致了独特的性质，其可以用作阅读MNW类型的签名，用于作为纳米条形码的应用。当在径迹蚀刻聚碳酸酯膜内合成时，所得的MNW嵌入膜可用作生物相容性绷带，用于在没有接触或光学瞄准的情况下进行检测。当从生长模板蚀刻出来时，自由浮动的MNW在37 °C下被细胞内化，使得可以收集和检测细胞和/或外来体。在冷冻保存应用中，MNW可以悬浮在冷冻保存剂（CPA）中，以便在组织和器官玻璃化至-200 °C时注射到组织和器官的血管中。使用交变磁场，MNW然后可以被快速地磁化以防止结晶，并且均匀地防止样品破裂，例如，作为移植物或移植物。这篇特邀论文是对MNW在条形码、生物复合材料和生物标记物等特定生物应用方面的最新进展的综述。
Magnetic nanowires (MNWs) can have their moments reversed via several mechanisms that are controlled using the composition, length, diameter, and density of nanowires in arrays as-synthesized or as individual nanoparticles in assays or gels. This tailoring of magnetic reversal leads to unique properties that can be used as a signature for reading out the type of MNW for applications as nano-barcodes. When synthesized inside track-etched polycarbonate membranes, the resulting MNW-embedded membranes can be used as biocompatible bandaids for detection without contact or optical sighting. When etched out of the growth template, free-floating MNWs are internalized by cells at 37 °C such that cells and/or exosomes can be collected and detected. In applications of cryopreservation, MNWs can be suspended in cryopreservation agents (CPAs) for injection into the blood vessels of tissues and organs as they are vitrified to −200 °C. Using an alternating magnetic field, the MNWs can then be nanowarmed rapidly to prevent crystallization and uniformly to prevent cracking of specimens, for example, as grafts or transplants. This invited paper is a review of recent progress in the specific bioapplications of MNWs to barcodes, biocomposites, and nanowarmers.