TSPY variants in six loci on the human Y chromosome
TSPY variants in six loci on the human Y chromosome
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DOI：
10.1159/000056821
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发表时间：
2000-01-01
期刊：
影响因子：
--
通讯作者：
Schmidtke, J
中科院分区：
文献类型：
--
作者：
Dechend, F;Williams, G;Schmidtke, J
We have studied the structure, organization, and evolution of the human TSPY gene family by mapping three sequence variants identified through RT-PCR analysis onto genomic clones derived from two different YAC contigs. TSPY gene family members occur in at least six locations on the human Y chromosome, and each cluster contains a unique combination of variants. Our data further suggest that an 18-bp tandem duplication found in TSPY exon 1 originated from an unequal sister chromatid exchange between two tandemly arranged TSPY clusters. Copyright (C) 2001 S. Karger AG, Basel.
