The African origin of Plasmodium vivax.
The African origin of Plasmodium vivax.
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间日疟原虫起源于非洲。
DOI：
10.1093/femsre/fuac015
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发表时间：
2022
影响因子：
11.3
通讯作者：
Hahn,BeatriceH
中科院分区：
文献类型：
--
作者：
Sharp,PaulM;Plenderleith,LindseyJ;Culleton,Richard;Hahn,BeatriceH
Rougeron和他的同事最近回顾了人类两种主要疟疾寄生虫--恶性疟原虫和间日疟原虫的起源(Rougeron等人。2021年)。他们用一棵进化树支持了他们的论点，该树旨在描述感染哺乳动物的疟原虫物种之间的关系。然而，他们提出的系统发展是基于过时的分析和一些(错误的)猜测。最近对更大的数据集的分析产生了不同的结果，这是正确解释间日疟原虫起源的关键。Rougeron等人(2021)在图1中显示的系统发育图，相关方面在图3中重复，被描述为“主要基于Galen等人(2018)的结果”。Galen等人(2018)对疟原虫和血孢子虫其他属之间的高级关系感兴趣，并使用了一个包含21种蛋白质的数据库，这些蛋白质在这一广泛的物种中保存。最近，几个小组利用质外体基因组编码的30个蛋白质序列，重点分析了感染哺乳动物的疟原虫物种(Arisue等人。2019年)，或由核基因组编码的1000多个蛋白质序列(Rutledge等人。2017年，夏普等人。这些研究在重要方面与Rougeron等人(2021)的图1所示的系统发育不同。
Rougeron and colleagues recently reviewed the origin of the two major human malaria parasites, Plasmodium falciparum and P. vivax (Rougeron et al. 2021). They supported their arguments with an evolutionary tree intended to depict the relationships among mammal-infecting Plasmodium species. However, the phylogeny they presented is based on outdated analyses, and some (erroneous) guesswork. More recent analyses of larger datasets have yielded different results, which are key for correctly interpreting the origins of P. vivax.The phylogeny shown by Rougeron et al.(2021) in Fig. 1, with relevant aspects repeated in Fig. 3, is described as ‘mostly based on the results of Galen et al.( 2018)’. Galen et al.(2018) were interested in the higher order relationships among Plasmodium and other genera of Haemosporidian parasites and used a dataset of 21 proteins conserved across this broad range of species. More recent analyses by several groups have focused on Plasmodium species infecting mammals, using 30 protein sequences encoded by the apicoplast genome (Arisue et al. 2019), or more than 1000 protein sequences encoded by the nuclear genome (Rutledge et al. 2017, Sharp et al. 2020); these studies have yielded results that differ from the phylogeny shown in Fig. 1 of Rougeron et al.(2021) in important ways.