Myocardial viability with chronic total occlusion assessed by hybrid positron emission tomography/magnetic resonance imaging
Myocardial viability with chronic total occlusion assessed by hybrid positron emission tomography/magnetic resonance imaging
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DOI：
10.1007/s12350-020-02041-3
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发表时间：
2020-01
影响因子：
2.4
通讯作者：
T. Kiko;T. Yokokawa;T. Misaka;Atsuro Masuda;A. Yoshihisa;T. Yamaki;H. Kunii;K. Nakazato;Y. Takeishi
中科院分区：
文献类型：
--
作者：
T. Kiko;T. Yokokawa;T. Misaka;Atsuro Masuda;A. Yoshihisa;T. Yamaki;H. Kunii;K. Nakazato;Y. Takeishi
背景本研究旨在比较18F-氟脱氧葡萄糖（FDG）摄取和晚期钆增强（LGE）透壁性与冠状动脉慢性完全闭塞（CTO）患者左室功能改善的关系，并通过FDG正电子发射断层扫描（PET）/磁共振成像（MRI）评估。23例患者随后接受经皮冠状动脉介入治疗（PCI），最终研究人群包括15例接受初始和随访MRI的患者。17个心肌节段中的每一个的壁运动异常的程度进行了评价的基础上，壁增厚的程度电影MRI使用5-pointscale.ResultsAmong所有646个心肌节段在基线，FDG摄取显着下降的transmartality的LGE是先进的。在接受PCI的15例患者中，152个节段在基线时显示室壁运动异常。PET-存活/MRI-存活节段的室壁运动异常的功能恢复最高，PET-非存活/MRI-非存活节段的室壁运动异常的功能恢复最低。PET-可行/MRI-不可行和PET-不可行/MRI-可行segments. ConclusionSimultaneousAssessment的FDG和LGE使用混合PET/MRI系统之间的功能恢复没有差异，可以帮助预测CTO患者PCI后的功能恢复。
BackgroundThe present study was performed to compare the relationship of18F-fluorodeoxyglucose (FDG) uptake and late gadolinium enhancement (LGE) transmurality with the improvement of left ventricular function in patients with coronary chronic total occlusion (CTO) assessed by hybrid FDG positron emission tomography (PET)/magnetic resonance imaging (MRI).MethodsThirty-eight consecutive patients with CTO underwent FDG PET/MRI. Twenty-three patients then underwent percutaneous coronary intervention (PCI), and the final study population comprised 15 patients who underwent both initial and follow-up MRI. The degree of wall motion abnormality in each of the 17 myocardial segments was evaluated based on the extent of wall thickening on cine MRI using a 5-point scale.ResultsAmong all 646 myocardial segments at baseline, FDG uptake significantly decreased as the transmurality of LGE is advanced. Of the 15 patients who underwent PCI, 152 segments showed wall motion abnormalities at baseline. The functional recovery of the wall motion abnormality of the PET-viable/MRI-viable segments was highest, and that of the PET-nonviable/MRI-nonviable segments was lowest. There were no differences in functional recovery between the PET-viable/MRI-nonviable and PET-nonviable/MRI-viable segments.ConclusionSimultaneous assessment of FDG and LGE using a hybrid PET/MRI system can help to predict functional recovery after PCI in patients with CTO.