RECURRENCE OF SPINAL EPENDYMOMA - RISK-FACTORS AND LONG-TERM SURVIVAL
RECURRENCE OF SPINAL EPENDYMOMA - RISK-FACTORS AND LONG-TERM SURVIVAL
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DOI：
10.1097/00007632-199412150-00019
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发表时间：
1994-12-15
期刊：
影响因子：
3
通讯作者：
CANTORE, G
中科院分区：
文献类型：
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作者：
CERVONI, L;CELLI, P;CANTORE, G
研究设计.对78例脊髓室管膜瘤进行了研究。作者将患者分为两组。其目的是找出复发的危险因素和接受二次手术的患者的命运。A组由59例随访时无复发迹象的患者组成（中位随访14年），B组由19例因复发而接受二次手术的患者组成（中位随访12年）。比较两组患者的临床、治疗特点及生存情况。分析表明，临床病史长短（P < 0.05）、首次手术时肿瘤外观（P <0.05）和手术方式（P < 0.001）是预测复发的最重要因素。这些因素被证明是密切相关的。如果复发，脊髓室管膜瘤预后不良。
Study Design. A study was conducted on 78 patients with spinal ependymoma. The authors divided the patients in two groups.Objectives. The aim was to elicit the risk factors for recurrence and the fate of patients who underwent second operations.Summary of Background Data. Group A is made up of 59 patients with no signs of recurrence at follow-up (median 14 years), and group B is made up of 19 patients who had undergone second operations because of relapses (follow-up median 12 years).Methods. The clinical and therapeutic characteristics and survival of the two groups were compared statistically.Result. Analysis of the series shows that the most important points in predicting recurrence are length of clinical history (P < 0.05), gross appearance of the tumor at first operation (P < 0.05), and type of excision (P < 0.001).Conclusion. These factors proved to be closely interrelated. In the event of recurrence, spinal ependymoma has an adverse prognosis.