PULMONARY HYPERTENSION WITH SPECIAL REFERENCE TO THE VASOCONSTRICTIVE FACTOR*

PULMONARY HYPERTENSION WITH SPECIAL REFERENCE TO THE VASOCONSTRICTIVE FACTOR*
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肺动脉高压,特别涉及血管收缩因素*

DOI:
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发表时间:
1958
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通讯作者:
P. Wood
P. Wood
中科院分区:
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作者:
P. Wood

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在心脏病研究所和布朗普顿医院研究的60名正常对照者的正常肺动脉压为16/7毫米汞柱(以胸骨角为基准),平均值为11毫米,范围为8/2-28/14毫米。平均心输出量为每分钟8升,通常范围为每分钟5 - 5升。左心房压力平均为2 - 3 mm Hg。因此,肺血管阻力约为1个单位或80达因秒,肺血管阻力的简单单位是肺动脉压减去左心房压(毫米汞柱)除以肺血流量(升/分钟)。cm.- 5.肺动脉高压的定义。肺动脉高压字面上意味着肺动脉血压高于30/15 mm,这是正常范围的上限。在实践中,严重的肺动脉高压通常意味着压力处于或接近全身水平,但很少超过150 mm。
The normal pulmonary blood pressure in a series of 60 normal controls studied at the Institute of Cardiology and at the Brompton hospital was 16/7 mm. Hg with reference to the sternal angle, the mean being 11 mm. and the range 8/2-28/14 mm. The mean cardiac output was 8 litres a minute, and the common range 5 5 to 10-5 litres a minute. The left atrial pressure averaged 2 to 3 mm. Hg. The pulmonary vascular resistance, which in simple units is the pulmonary artery pressure minus the left atrial pressure in mm. Hg divided by the pulmonary blood flow in litres a minute, was therefore about 1 unit or 80 dynes sec./cm.-5. Definition of Pulmonary Hypertension. Pulmonary hypertension literally implies a pulmonary blood pressure above 30/15 mm. which is the upper limit of the normal range. In practice serious pulmonary hypertension usually means a pressure at or around systemic level, but rarely in excess of 150 mm.