Carbon Ion Radiotherapy at the Gunma University Heavy Ion Medical Center: New Facility Set-up.
Carbon Ion Radiotherapy at the Gunma University Heavy Ion Medical Center: New Facility Set-up.
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DOI：
10.3390/cancers3044046
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发表时间：
2011-10-26
期刊：
影响因子：
5.2
通讯作者：
Nakano T
中科院分区：
文献类型：
--
作者：
Ohno T;Kanai T;Yamada S;Yusa K;Tashiro M;Shimada H;Torikai K;Yoshida Y;Kitada Y;Katoh H;Ishii T;Nakano T
与传统的x线治疗相比，碳离子放射治疗（C-ion RT）在治疗深部肿瘤方面具有更好的剂量一致性。此外，与质子或x射线束相比，碳离子束具有更高的相对生物有效性。群马大学重离子医学中心（GHMC）于2010年3月开始对第一位患者进行c离子放射治疗。该设施的主要规格是根据美国国家放射科学研究所（NIRS）的临床治疗经验确定的，其规模和成本减少到NIRS的三分之一。目前GHMC癌症治疗的指示部位是肺、前列腺、头颈部、肝脏、直肠、骨骼和软组织。在2010年3月至2011年7月期间，GHMC共治疗了177例患者，尽管在考虑最佳机器性能的期间，总共有100例患者是设计规范。本文介绍了GHMC的设施设置，包括设施设计、治疗计划系统和临床准备。
Carbon ion radiotherapy (C-ion RT) offers superior dose conformity in the treatment of deep-seated tumors compared with conventional X-ray therapy. In addition, carbon ion beams have a higher relative biological effectiveness compared with protons or X-ray beams. C-ion RT for the first patient at Gunma University Heavy Ion Medical Center (GHMC) was initiated in March of 2010. The major specifications of the facility were determined based on the experience of clinical treatments at the National Institute of Radiological Sciences (NIRS), with the size and cost being reduced to one-third of those at NIRS. The currently indicated sites of cancer treatment at GHMC are lung, prostate, head and neck, liver, rectum, bone and soft tissue. Between March 2010 and July 2011, a total of 177 patients were treated at GHMC although a total of 100 patients was the design specification during the period in considering the optimal machine performance. In the present article, we introduce the facility set-up of GHMC, including the facility design, treatment planning systems, and clinical preparations.