Calf circumference as a surrogate marker of muscle mass for diagnosing sarcopenia in Japanese men and women
Calf circumference as a surrogate marker of muscle mass for diagnosing sarcopenia in Japanese men and women
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DOI：
10.1111/ggi.12377
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发表时间：
2015-08-01
影响因子：
3.3
通讯作者：
Miyachi, Motohiko
中科院分区：
文献类型：
--
作者：
Kawakami, Ryoko;Murakami, Haruka;Miyachi, Motohiko
AimTo检查小腿周长和肌肉质量之间的关系，并评估小腿周长作为肌肉质量的替代标记的诊断肌肉减少症的中年和老年日本男性和女性之间的适合性。MethodsA共526名40-89岁的成年人参加了本横断面研究。在站立位测量最大小腿围。采用双能X线骨密度仪测量骨骼肌重量，骨骼肌指数计算为骨骼肌重量除以身高的平方（kg/m2）。肌肉减少症的截止值被定义为骨骼肌指数小于-2标准偏差的平均值为日本年轻人，如前所述，ResultsCalf周长与apapricular骨骼肌（r=0.81在男性，r=0.73在女性）和骨骼肌指数（r=0.80在男性，r=0.69在女性）呈正相关。在受试者操作特征分析中，预测肌少症的最佳小腿围界值为34 cm（敏感性88%，特异性91%），男性和33 cm结论小腿围度与围外骨骼肌质量和骨骼肌指数呈正相关，并可用作诊断肌肉减少症的肌肉质量的替代标志物。小腿围预测低肌肉质量的建议截止值为
AimTo examine the relationship between calf circumference and muscle mass, and to evaluate the suitability of calf circumference as a surrogate marker of muscle mass for the diagnosis of sarcopenia among middle-aged and older Japanese men and women.MethodsA total of 526 adults aged 40-89 years participated in the present cross-sectional study. The maximum calf circumference was measured in a standing position. Appendicular skeletal muscle mass was measured using dual-energy X-ray absorptiometry, and the skeletal muscle index was calculated as appendicular skeletal muscle mass divided by the square of the height (kg/m(2)). The cut-off values for sarcopenia were defined as a skeletal muscle index of less than -2 standard deviations of the mean value for Japanese young adults, as defined previously.ResultsCalf circumference was positively correlated with appendicular skeletal muscle (r=0.81 in men, r=0.73 in women) and skeletal muscle index (r=0.80 in men, r=0.69 in women). In receiver operating characteristic analysis, the optimal calf circumference cut-off values for predicting sarcopenia were 34cm (sensitivity 88%, specificity 91%) in men and 33cm (sensitivity 76%, specificity 73%) in women.ConclusionsCalf circumference was positively correlated with appendicular skeletal muscle mass and skeletal muscle index, and could be used as a surrogate marker of muscle mass for diagnosing sarcopenia. The suggested cut-off values of calf circumference for predicting low muscle mass are