Genetic Strain-Dependent Protein Metabolism and Muscle Hypertrophy Under Chronic Isometric Training in Rat Gastrocnemius Muscle
Genetic Strain-Dependent Protein Metabolism and Muscle Hypertrophy Under Chronic Isometric Training in Rat Gastrocnemius Muscle
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DOI：
10.33549/physiolres.932312
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发表时间：
2012-01-01
影响因子：
2.1
通讯作者：
Nakazato, K.
中科院分区：
文献类型：
--
作者：
Kobayashi, K.;Ogasawara, R.;Nakazato, K.
大鼠骨骼肌对机械刺激的遗传品系依赖性反应性尚未得到检验。本研究旨在研究遗传菌株依赖是否与等长阻力训练（RD）后蛋白质代谢的反应性和由此产生的肌肉肥大有关。Sprague-Dawley （SD）和Wistar大鼠的右三头肌进行了12次RT。RT后，两种菌株都观察到从lib到IIx肌球蛋白重链亚型的转变。SD大鼠训练腿（TRN）腓肠肌外侧肌（LG）质量显著高于对照组（CON） (7.8%， P
Genetic strain-dependent reactivity to mechanical stimuli in rat skeletal muscle has not been examined. This study aimed to examine whether genetic strain-dependency is associated with reactivity in protein metabolism and the resultant muscle hypertrophy after isometric resistance training (RD. The right triceps of Sprague-Dawley (SD) and Wistar rats underwent 12 sessions of RT. After RT, a transition from the lib to the IIx myosin heavy-chain isoform was observed in both strains. In SD rats, the lateral gastrocnemius muscle (LG) mass of the trained legs (TRN) was significantly higher than that of the control legs (CON) (7.8 %, P