PLASMID-ENCODED MULTIPLE ANTIBIOTIC RESISTANCE IN VIBRIO CHOLERÆ EL TOR FROM BANGLADESH
PLASMID-ENCODED MULTIPLE ANTIBIOTIC RESISTANCE IN VIBRIO CHOLERÆ EL TOR FROM BANGLADESH
复制标题
孟加拉国霍乱弧菌中质粒编码的多重抗生素耐药性
DOI：
10.1016/s0140-6736(80)91701-8
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发表时间：
1980
期刊：
影响因子：
--
通讯作者：
I. Huq
中科院分区：
文献类型：
--
作者：
E. Threlfall;B. Rowe;I. Huq
在孟加拉国分离到对多种抗生素耐药的O群1型El Tor霍乱弧菌菌株：季节性暴发的第一个月有5%的菌株，但到第4个月高达36%。抗性是质粒编码的，并遇到3个R型抗性。耐药谱包括氨苄西林、卡那霉素、链霉素、大观霉素、四环素类、磺胺类和甲氧苄啶。还有其他由V菌株引起的霍乱爆发。C组质粒编码多重耐药的霍乱弧菌，可能是C组质粒对V具有特殊的亲和性。胆汁。虽然四环素类抗生素可用于治疗霍乱病人，但由于存在出现耐药性的危险，用抗生素进行大规模预防可能不太被接受。B。克莉丝汀
Strains of O group 1Vibrio choleraebiotype El Tor resistant to multiple antibiotics were isolated in Bangladesh: 5% of strains in the first month ofthe seasonal outbreak, but up to 36% by the 4th month. The resistance was plasmid-encoded and 3 R types of resistance were encountered. The resistance spectrum covered ampicillin, kanamycin, streptomycin, spectinomycin, tetracyclines, sulphonamides and trimethoprim. There have been other outbreaks pf cholera caused by strains ofV. choleraein which multiple resistances were encoded by a group C plasmid and it may be that group C plasmids have a special affinity forV. cholerae. Whereas tetracyclines may be indicated in the treatment of patients with cholera, mass prophylaxis with antibiotics may be less acceptable because of the danger of the emergence of resistance.A. B. Christie.