Case of early gastric cancer with nodular gastritis

Case of early gastric cancer with nodular gastritis
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早期胃癌合并结节性胃炎一例

DOI:
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发表时间:
2004
期刊:
影响因子:
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通讯作者:
Y. Sadahira
Y. Sadahira
中科院分区:
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文献类型:
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作者:
T. Kamada;K. Haruma;K. Sugiu;Yuichi Nagashima;D. Qian;H. Koga;M. Takeda;H. Kusunoki;K. Honda;Y. Fujimura;T. Tsunoda;Y. Sadahira

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本文报告1例凹陷型早期胃癌合并结节性胃炎。1例47岁日本男性患者被转诊至本院接受胃癌手术治疗。上消化道检查和胃镜检查显示下体前壁有一4 5 × 3 0 cm凹陷性病变,并有一深中央溃疡。内窥镜下在胃窦内观察到一种不寻常的类似鹅肉的粟粒图案。肿瘤活检标本显示为低分化腺癌,胃窦标本显示许多淋巴滤泡和生发中心。免疫球蛋白G抗体和幽门螺杆菌组织学检查(Giemsa染色)均为阳性。诊断为早期胃癌合并结节性胃炎,行胃大部切除术。组织学检查显示,I期肿瘤浸润性低分化腺癌,伴有体部凹陷性病变(0、IIc、 + 、III型)和胃窦部结节性胃炎。术后1年,患者情况良好。
A case of depressed early gastric cancer with nodular gastritis is described. A 47‐year‐old Japanese man was referred to our hospital and admitted for surgical treatment of gastric cancer. Barium upper gastrointestinal study and endoscopy examination showed a 4.5 × 3.0 cm depressed lesion with a deep central ulceration in the anterior wall of the lower corpus. An unusual miliary pattern resembling ‘goose flesh’ was observed endoscopically in the antrum. Biopsy specimens from the tumor showed poorly differentiated adenocarcinoma, and specimens from the antrum showed many lymphoid follicles with a germinal center. Immunoglobulin G antibody and histological tests (Giemsa stain) for Helicobacter pylori were both positive. Early gastric cancer with nodular gastritis was diagnosed and a subtotal gastrectomy was performed. Histological examination of the resected specimen showed a stage I tumor infiltrating a poorly differentiated adenocarcinoma with a depressed lesion in the corpus (type 0 IIc + III) and nodular gastritis in the antrum. The patient is doing well 1 year after surgery.